| 福建爱德华氏菌对土霉素、氯霉素和链霉素的感受性、耐药性研究 |
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| 引用本文： | 陈昌福,毛芝娟,王敏.福建爱德华氏菌对土霉素、氯霉素和链霉素的感受性、耐药性研究[J].淡水渔业,1996,26(3):3-6. |
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| 作者姓名： | 陈昌福 毛芝娟 王敏 |
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| 作者单位： | 华中农业大学水产学院 |
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| 摘 要： | 本研究在试管内测定福建爱德华氏菌对土霉素、氯霉素和链霉素的最小抑菌浓度分别为５０ｕｇ／ｍｌ，３．１２ｕｇ／ｍｌ和０．３９ｕｇ／ｍｌ。在２５℃下经药物浓度递增继代培养，该菌株对这３种抗生素的最小抑菌浓度分别上升了１６倍，３２倍和６４倍。而对已获得耐药性的菌株进行无添加药物继代培养９次、１２次和１１次后，对土霉素、氯霉素和链霉素的敏感性又回复到了初始水平。
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| 关 键 词： | 福建爱德华氏菌，抗生素，最小抑菌浓度，耐药性 |
CHARACTERISTICS OF EDWARDSIELLA FUJIANESIS TO THREE ANTIBOTIC |
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| Chen Changfu,Mao Zhi Juan,and Wang Min.CHARACTERISTICS OF EDWARDSIELLA FUJIANESIS TO THREE ANTIBOTIC[J].Freshwater Fisheries,1996,26(3):3-6. |
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| Authors: | Chen Changfu Mao Zhi Juan and Wang Min |
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| Abstract: | This paper reports in vitro sensitivity and development of drug-resistance characteristics of Edwardsiella fujianesis against oxytetracycline(OTC),chloramphenic(CP)and sreptomycin(SM).Theminimum inhibitory concentration(MIC)of OTC,CP and SM were 50μg/ml,3.12μg/ml and 0.39μg/ml respectively.After 10 serial passages in vitro under the presence of drugs,MIC values to OTC CP and SM were 16,32 and 64 times greater than the initial values.Reversion of acquired drug-resistance features to drugs also were studied.After 9,12 and 11 serial passages in vitro under the absence of the drugs the acquired drug -resistance characteristics of E.fujianesis disappeared. |
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| Keywords: | Edwardsiella fujianesis antibiotic MIC drug-resistance |
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