| 黄芩素对鲤肝细胞及肝胰脏组织CAT、GST和MDA水平影响的初步研究 |
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| 引用本文： | 吉红,曹福余,周继术.黄芩素对鲤肝细胞及肝胰脏组织CAT、GST和MDA水平影响的初步研究[J].淡水渔业,2008,38(3). |
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| 作者姓名： | 吉红 曹福余 周继术 |
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| 作者单位： | 西北农林科技大学动物科技学院,陕西杨凌,712100 |
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| 基金项目： | 国家留学基金委留学归国人员科研启动基金，西北农林科技大学校科研和教改项目 |
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| 摘 要： | 采用处理离体培养的细胞和对鱼灌服方法分别研究了黄芩素对鲤(Cyprinus carpio)肝细胞以及肝胰脏过氧化氢酶(CAT)、谷胱甘肽-S转移酶(GST)、丙二醛(MDA)的影响。结果显示:黄芩素处理2h后,鲤肝细胞GST活性显著高于对照组(P<0.05),8h时细胞CAT活性极显著高于对照组(P<0.01);灌服黄芩素后,32h时,鲤肝胰脏CAT活性显著高于对照组(P<0.05)。研究表明,黄芩素可以有效地提高鲤抗氧化酶GST和CAT的活性。
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| 关 键 词： | 黄芩素 鲤(Cyprinus carpio) 肝 抗氧化酶 |
Preliminary Study on the Effects of Baicalein on CAT, GST and MDA in Hepatocytes and Hepatopancrease of Cyprinus carpio |
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| JI Hong,CAO Fu-yu,ZHOU Ji-shu.Preliminary Study on the Effects of Baicalein on CAT, GST and MDA in Hepatocytes and Hepatopancrease of Cyprinus carpio[J].Freshwater Fisheries,2008,38(3). |
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| Authors: | JI Hong CAO Fu-yu ZHOU Ji-shu |
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| Abstract: | To evaluate the effect of baicalein on the antioxidant activity in hepatocytes and hepatopancrease ofCyprinus carpio.The results showed that catalase(CAT)activity in hepatocytes of C.carpio treated with baicalein was remarkable higher than that in untreated hepatocytes at 8 h(P<0.01),and the CAT activity in hepatopancrease of C.carpio which were orally administrated with baicalein was significantly higher than that of control group(P<0.05);baicalein also increased the activity of GST in hepatocytes of C.carpio.In conclusion,baicalein could increase the activity of the antioxidant enzymes. |
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| Keywords: | baicalein Cyprinus carpio liver antioxidant enzyme |
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