普洱茶对高脂实验大鼠肝脏病理的影响

为探讨普洱茶对高脂饮食大鼠肝脏病理组织形态学的影响,将SD大鼠分为正常对照组、高脂模型组以及低、中、高剂量(即0.5、1.5、3.0g/kg)的普洱生茶、普洱熟茶组,共8组。进行为期30d的灌胃后,将试验大鼠处死,进行肝脏病理组织学的检测,并测定了试验大鼠血清中的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)等血脂指标。结果发现,摄入普洱茶后,实验大鼠能够以剂量依赖方式梯度性地改善高脂饲料引起的肝脏脂肪变性,同时具有降低高脂血症大鼠血脂的作用。

Effect of Pu-erh Tea on Liver Pathology of High-fat Rats

To investigate the effect of Pu-erh tea on liver pathology of high-fat rats,SD rats were divided into eight groups,namly control group,hyperlipidemia model group,and six dose groups including the low,medium and high doses groups of fermented Pu-erh tea and unfermented Pu-erh tea(0.5 g/kg,1.5 g/kg,3.0 g/kg).After administered by gavage for 30 d,the rats were sacrificed and the liver pathology was observed.Simultaneously,the level of TC,TG and HDL-C in blood were determined.The result showed that after given the Pu-erh tea,hepatic steatosis caused by high-fat diet in rats had been improved correspondingly in a dose-dependent manner and the blood-fat of rats with hyperlipidemia was reduced remarkably.