|
|||||
|
|
| 绿茶EGCG防癌作用的分子靶点 | |
| 引用本文： | 顾成波,袁肖寒,付玉杰,祖元刚,赵恩泽,李旺,王秋雪.绿茶EGCG防癌作用的分子靶点[J].茶叶科学,2010,30(6). |
| 作者姓名： | 顾成波 袁肖寒 付玉杰 祖元刚 赵恩泽 李旺 王秋雪 |
| 作者单位： | 1. 东北林业大学森林植物生态学教育部重点实验室,黑龙江,哈尔滨,150040;东北林业大学林业生物制剂教育部工程研究中心,黑龙江,哈尔滨,150040;浙江海正药业股份有限公司,浙江,台州,318000 2. 东北林业大学林学院,黑龙江,哈尔滨,150040;东北农业大学生命科学与生物技术研究中心,黑龙江,哈尔滨,150030 3. 东北林业大学森林植物生态学教育部重点实验室,黑龙江,哈尔滨,150040;东北林业大学林业生物制剂教育部工程研究中心,黑龙江,哈尔滨,150040 |
| 基金项目： | 国家科技支撑计划资助项目(2006BAD18B0401); 中央高校基本科研业务费专项资金(DL09BA20); 东北林业大学青年科研基金(07030) |
| 摘 要： | 表没食子儿茶素没食子酸酯(EGCG)是绿茶中含量最高、活性最强的多酚类成分。近年来绿茶EGCG癌症预防作用的分子靶点一直备受关注。本文对已报道的EGCG癌症预防作用机制及其可能的作用靶点进行了综述,讨论了将EGCG开发为癌症化学预防剂应采取的策略,以期为设计预防癌症的新方案提供借鉴。 |
| 关 键 词： | EGCG 癌症化学预防 分子机制 分子靶点 |
Molecular Targets for Cancer Chemoprevention by (-)-Epigallocatechin Gallate of Green Tea |
|
| GU Cheng-bo,YUAN Xiao-han,FU Yu-jie,ZU Yuan-gang,ZHAO En-ze,LI Wang,WANG Qiu-xue.Molecular Targets for Cancer Chemoprevention by (-)-Epigallocatechin Gallate of Green Tea[J].Journal of Tea Science,2010,30(6). | |
| Authors: | GU Cheng-bo YUAN Xiao-han FU Yu-jie ZU Yuan-gang ZHAO En-ze LI Wang WANG Qiu-xue |
| Institution: | GU Cheng-bo 1,2,5,YUAN Xiao-han 3,4,FU Yu-jie 1,ZU Yuan-gang 1,ZHAO En-ze 1,LI Wang 1,WANG Qiu-xue 1,2(1.Key Laboratory of Forest Plant Ecology,Ministry of Education,Northeast Forestry University,Harbin 150040,China,2.Engineering Research Center of Forest Bio-preparation,3.College of Forestry,4.Life Science , Biotechnique Research Center,Northeast Agricultural University,Harbin... |
| Abstract: | (-)-Epigallocatechin gallate(EGCG) is the most active and major polyphenolic compound in green tea. The molecular mechanisms and targets on the action of EGCG have been extensively investigated.This paper reviewed some of the reported mechanisms and possible targets for the action of EGCG,and strategies for cancer chemoprevention by EGCG in clinical trials were discussed.It provides a new inspiration for cancer chemoprevention. |
| Keywords: | EGCG cancer chemoprevention molecular mechanisms molecular targets |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |