基于便携式生物传感器设备的转基因现场快速分析研究

现场快速检验（point of care test, POCT）是实现转基因基层监管必要的技术手段，在转基因成分检测中发 挥着重要作用。生物传感器为转基因成分简单、快速和低成本定量分析提供了一个可行的技术方案。目前大量的 生物传感器研究还处于方法学研究阶段，研究者需要着重将生物传感器技术与分析设备集成，开发小型化的便携 式检测系统，从而满足POCT分析。本文回顾了近年来已开发的基于手持式设备的用于转基因POCT分析的微型生 物传感器系统研究进展，提出了未来可用于转基因POCT分析的生物传感器的小型化策略，展望了小型化转基因生 物传感器系统的发展趋势、发展前景和面临的挑战。

Advances in portable biosensor devices for point-of-care test of genetically modified crops

Point-of-care test(POCT)is a necessary technology to implement the supervision of genetically modified(GM)crops in resource-limited settings,which plays an important role in GM organisms monitoring.Recently,biosensor provides a promising pathway for a simple,quick and affordable quantification of GM ingredients.So far plenty of studies have concentrated on the methodology development of biosensor,however its application has rarely been reported.The development of portable biosensors with desirable characteristics of integration and miniaturization is highly demand for POCT.This paper reviews recent advances in handheld device-assisted miniaturized biosensor systems for POCT of GM crops.Miniaturization strategies of biosensors for POCT of GM organisms in the future are then proposed.The trends,prospects and challenges of miniaturized biosensors for POCT are further described.