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In vitro antimicrobial activity of different accessions ofSolanum commersonii Dun. from Uruguay
Authors:M I Siri  P Villanueva  M J Pianzzola  L Franco Fraguas  G Galván  M Acosta  F Ferreira
Institution:(1) Facultad de Química, Cátedra de Microbiología, Uruguay;(2) Departamento Química Orgńica, Facultad de Química, Laboratorio de Carbohidratos y Glicoconjugados, Uruguay;(3) Facultad de Química, Cátedra de Bioquímica, CC 1157 Montevideo, Uruguay;(4) Facultad de Agronomía, Departamento de Producción Vegetal, Montevideo, Uruguay
Abstract:Summary The in vitro antimicrobial activity of extracts from accessions ofSolanum commersonii Dun. collected in the south of Uruguay was investigated against five microorganisms including the pathogenRalstonia solanacearum. A total of 30 extracts corresponding to organic and aqueous extracts were studied. Interestingly, most of the positive results for growth inhibition were againstR. solanacearum. The extracts were also analyzed for the presence of glycoalkaloids and lectins. Six of the ten aqueous extracts showed lectin presence and a wide variation in the type and amounts of glycoalkaloids, was found. Results indicate that there is no clear relationship between the antimicrobial activity against the five microorganisms screened and the presence or amounts of lectins and glycoalkaloids, traditionally regarded as possible antimicrobial metabolites in theSolanum genus, which indicates the presence of as yet unidentified antimicrobial compounds.
Keywords:Solanum commersonii                      Ralstonia solanacearum                      Staphylococcus aureus                      Escherichia coli                      Candida albicans                      Penicillium expansum            glycoalkaloids  lectins
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