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| 硫磺菌菌丝体粗多糖对小鼠Lewis肺癌的体内抑制 | |
| 引用本文： | 闫梅霞,关一鸣,胡清秀,张瑞,王英平,杨元超.硫磺菌菌丝体粗多糖对小鼠Lewis肺癌的体内抑制[J].食用菌学报,2011,18(1). |
| 作者姓名： | 闫梅霞 关一鸣 胡清秀 张瑞 王英平 杨元超 |
| 作者单位： | 1. 中国农业科学院农业资源与农业区划研究所,北京1000812;中国农业科学院特产研究所,吉林吉林132109 2. 中国农业科学院特产研究所,吉林吉林,132109 3. 中国农业科学院农业资源与农业区划研究所,北京,1000812 |
| 基金项目： | 由国家现代食用菌产业技术体系的岗位专家专项经费资助 |
| 摘 要： | 对硫磺菌(Laetiporus sulphureus)液体发酵菌丝粗多糖进行体内抗肿瘤研究,结果表明:硫磺菌粗多糖对Lewis肺癌的体内最大抑制作用为35.7%,粗多糖组对胸腺和脾脏的影响显著小于环磷酰胺. |
| 关 键 词： | 液体发酵 粗多糖 抗肿瘤 |
Antitumor Activity of Crude Polysaccharide from Laetiporus sulphureus |
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| YAN Meixia,GUAN Yiming,HU Qingxiu,ZHANG Rui,WANG Yingping,YANG Yuanchao.Antitumor Activity of Crude Polysaccharide from Laetiporus sulphureus[J].Acta Edulis Fungi,2011,18(1). | |
| Authors: | YAN Meixia GUAN Yiming HU Qingxiu ZHANG Rui WANG Yingping YANG Yuanchao |
| Institution: | YAN Meixia1,2,GUAN Yiming2,HU Qingxiu1,ZHANG Rui2,WANG Yingping2,YANG Yuanchao21Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 100081,China,2Institute of Special Wild Economic Animal and Plant Science,Jilin,Jilin 132109 |
| Abstract: | The antitumor activity of crude polysaccharide from Laetiporus sulphureus mycelium grown in submerged cultured was determined using Lewis lung cancer-bearing mice as the test model.Inhibitory effects on tumor growth were highest(35.7%) in mice administered 100 mg/mL of crude polysaccharide.However,spleen and thymus indices and animal weights were significant higher in polysaccharide-treated mice compared to positive control mice administered cyclophosphamide. |
| Keywords: | Submerged culture crude polysaccharide antitumor activity |
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