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| 非扫描式光学SPR生物传感器的数据分析 | |
| 引用本文： | 赵媛媛,肖龙,朱莺,胡建东,江敏,胡枫江,魏文松,李会芹.非扫描式光学SPR生物传感器的数据分析[J].河南农业大学学报,2011,45(3):323-327. |
| 作者姓名： | 赵媛媛 肖龙 朱莺 胡建东 江敏 胡枫江 魏文松 李会芹 |
| 作者单位： | 1. 河南农业大学机电工程学院,河南郑州,450002 2. 河南职业技术学院,河南郑州,450046 3. 浙江省标准化研究院,浙江杭州,310006 4. 河南农业大学生命科学学院,河南郑州,450002 |
| 基金项目： | 河南省教育厅创新人才项目(2009HASTIT019); 河南省杰出青年基金项目(104100510017); 郑州市科技领军人才项目(096SYJH25101) |
| 摘 要： | 提出了一种用于求解非扫描式光学SPR共振反射光谱信号的共振像素位点的最小二乘法多项式拟合方法,最大限度地提高信噪比.描述了滑动平均值滤波、多项式数据拟合方法的原理和共振反射光谱最低点的质心算法.采用体积分数为13％,14％,16％,17％,18％,19％的乙醇溶液进行试验验证.结果表明,多项式拟合算法对光功率变化等环境... |
| 关 键 词： | 表面等离子共振 生物传感器 非扫描 多项式拟合 质心法 |
Data analyses of a non-scanning optical biosensor based on surface plasmon resonance |
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| ZHAO Yuan-yuan,XIAO Long,ZHU Ying,HU Jian-dong,JIANG Min,HU Feng-jiang,WEI Wen-song,LI Hui-qin.Data analyses of a non-scanning optical biosensor based on surface plasmon resonance[J].Journal of Henan Agricultural University,2011,45(3):323-327. | |
| Authors: | ZHAO Yuan-yuan XIAO Long ZHU Ying HU Jian-dong JIANG Min HU Feng-jiang WEI Wen-song LI Hui-qin |
| Institution: | ZHAO Yuan-yuan1,XIAO Long2,ZHU Ying3,HU Jian-dong1,JIANG Min4,HU Feng-jiang1,WEI Wen-song1,LI Hui-qin1(1.College of Mechanical and Electrical Engineering,Henan Agricultural University,Zhengzhou 450002,China,2.Henan Vocational and Technical College,Zhengzhou 450046,3.Zhejiang Institute of Standardization,Hangzhou 310006,4.College of Life Sciences,China) |
| Abstract: | This paper proposes a novel design method of optical surface plasmon resonance biosensor in which a laser linear generator was used as a light source of the bioanalyzer,suggesting under appropriate assumptions,an optimal analysis fitting method derived for measuring biomolecular interaction parameters,and a centroid arithmetic for calculating the resonance dip position of a reflected spectra for an decrease in signal to noise ratio.A series of experiments were designed to validate the performance of the opt... |
| Keywords: | surface plasmon resonance biosensor non-scanning polynomial fit centroid method |
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