| 改进的光学表面等离子共振角度光谱分析方法 |
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| 引用本文： | 赵媛媛,蒋国良,高献坤,胡建东,胡敬芳,张润娜,汪兴莉.改进的光学表面等离子共振角度光谱分析方法[J].河南农业大学学报,2009,43(5). |
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| 作者姓名： | 赵媛媛 蒋国良 高献坤 胡建东 胡敬芳 张润娜 汪兴莉 |
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| 作者单位： | 1. 河南农业大学,河南,郑州,450002
2. 河南农大迅捷测试技术有限公司,河南,郑州,450002 |
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| 基金项目： | 国家863计划项目，河南省教育厅创新人才基金项目 |
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| 摘 要： | 提出了一种新颖的最大响应差调制方法,从理论和试验方面对比分析了角度调制和最大响应差调制的灵敏度,可以实现快速寻找共振位点.结果表明,基于最大响应差的快速共振位点寻找方法,不仅共振位点获得时间大大缩短,而且还提高了光学表面等离子共振生物分析仪的灵敏度.
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| 关 键 词： | 光学表面等离子共振 角度调制 最大响应差 灵敏度 |
Modified spectral analytical method of an optical surface plasmon resonance biosensor using angular interrogation |
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| ZHAO Yuan-yuan,JIANG Guo-liang,GAO Xian-kun,HU Jian-dong,HU Jing-fang,ZHANG Run-na,WANG Xing-li.Modified spectral analytical method of an optical surface plasmon resonance biosensor using angular interrogation[J].Journal of Henan Agricultural University,2009,43(5). |
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| Authors: | ZHAO Yuan-yuan JIANG Guo-liang GAO Xian-kun HU Jian-dong HU Jing-fang ZHANG Run-na WANG Xing-li |
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| Abstract: | The paper introduces a novel intensity interrogation based on a maximal response difference value to improve the sensitivity of the SPR biosensor and presents a theoretical analysis and comparison of the sensitivity and measurement system of these two types of SPR biosensors when employed in both of the angular interrogation and maximal response difference interrogation. The results show that this method of rapid location of the resonance point, which is based on the maxinal response difference value can not only significantly reduce the time for obtaining the resonance point, but also enhance the sensitivity of the optical surface plasmon resonance biosensors. |
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| Keywords: | optical surface plasmon resonance angular interrogation maximal response difference value sensitivity |
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