| 中国南方荷斯坦奶牛TRAPPC9、DGAT1、GHR、ATP1A1基因多态性与产奶性状相关性分析 |
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| 引用本文： | 王凯,柳广斌,黄特民,吴珍芳,孙宝丽,刘德武.中国南方荷斯坦奶牛TRAPPC9、DGAT1、GHR、ATP1A1基因多态性与产奶性状相关性分析[J].华南农业大学学报,2016,37(4):7-12. |
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| 作者姓名： | 王凯 柳广斌 黄特民 吴珍芳 孙宝丽 刘德武 |
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| 作者单位： | 1. 华南农业大学 动物科学学院 /畜禽育种国家地方联合工程研究中心,广东 广州,510642;2. 深圳市晨光乳业有限公司,广东 深圳,518107 |
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| 基金项目： | 深圳市战略新兴产业发展专项（JSGG20141118161353890）；温氏基金项目 |
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| 摘 要： | 【目的】研究转运蛋白颗粒复合体9(TRAPPC9)、二酰甘油酰基转移酶(DGAT1)、Na~+,K~+-ATP酶(ATP1A1)和生长激素受体(GHR)基因SNP座位多态性与我国南方荷斯坦奶牛Holstein cattle群体产奶性状的相关性。【方法】利用飞行质谱基因分型技术对SNP座位进行多态性检测,使用SAS软件进行统计分析。【结果】TRAPPC9基因rs110017379座位多态性对乳蛋白率和乳脂率有显著影响(P0.05);DGAT1基因rs109421300座位多态性对乳脂率有显著影响(P0.05);ATP1A1基因rs110256520座位多态性对乳蛋白率有显著影响(P0.05);GHR基因rs41639260座位多态性对乳蛋白率有显著影响(P0.05),对乳脂率有显著影响(P0.05)。【结论】可以考虑将TRAPPC9、DGAT1、ATP1A1和GHR基因相关SNP应用到我国南方荷斯坦奶牛的分子标记辅助选择工作中。
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| 关 键 词： | 中国荷斯坦奶牛 产奶性状 基因 SNP 分子标记 |
| 收稿时间： | 2015/12/4 0:00:00 |
Associations of polymorphisms in TRAPPC9,DGAT1,ATP1A1 and GHR genes with milk production traits in Holstein dairy cow in Southern China |
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| WANG Kai,LIU Guangbin,HUANG Temin,WU Zhenfang,SUN Baoli and LIU Dewu.Associations of polymorphisms in TRAPPC9,DGAT1,ATP1A1 and GHR genes with milk production traits in Holstein dairy cow in Southern China[J].Journal of South China Agricultural University,2016,37(4):7-12. |
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| Authors: | WANG Kai LIU Guangbin HUANG Temin WU Zhenfang SUN Baoli and LIU Dewu |
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| Institution: | 1 College of Animal Science, South China Agricultural University/ National & Local Joint Engineering Research Center for Breeding Animal Industry,,1 College of Animal Science, South China Agricultural University/ National & Local Joint Engineering Research Center for Breeding Animal Industry,,2 Shenzhen Chenguang Dairy Co.,Ltd.,,1 College of Animal Science, South China Agricultural University/ National & Local Joint Engineering Research Center for Breeding Animal Industry,,1 College of Animal Science, South China Agricultural University/ National & Local Joint Engineering Research Center for Breeding Animal Industry, and 1 College of Animal Science, South China Agricultural University/ National & Local Joint Engineering Research Center for Breeding Animal Industry, |
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| Abstract: | Objective] To study whether SNPs of TRAPPC9 , DGAT1 , ATP1 A1 and GHR genes were associated with milk production traits in Holstein dairy cow in Southern China. Method]The Sequenom MassARRAY IPLEX genotyping technology was applied for SNP genotyping, and SAS software was used for statistical analysis.Result]The association analysis showed that the rs110017379 SNP of TRAPPC9 had significant effects on protein percentage(PP) and fat percentage(FP)(P<0. 05), the rs109421300 of DGAT1 had significant effects on FP ( P<0. 05 ) , the rs110256520 of ATP1 A1 had significant effects on PP ( P<0. 05 ) , and the rs41639260 of GHR had significant effects on both PP and FP ( P<0. 05 ) .Conclusion]The SNPs of TRAPPC9 , DGAT1 , ATP1 A1 and GHR genes can be used in molecular marker assisted selection of Holstein dairy cow in Southern China. |
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| Keywords: | Chinese Holstein cow milk production trait gene SNP molecular marker |
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