| 紫苏叶提取物对高脂血症家兔血脂及脂质过氧化的影响 |
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| 引用本文： | 谭健民,陈眷华,徐在品,霍欣,邓小燕,张迪,简秀华.紫苏叶提取物对高脂血症家兔血脂及脂质过氧化的影响[J].农业科学与技术,2008,9(1):121-124. |
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| 作者姓名： | 谭健民 陈眷华 徐在品 霍欣 邓小燕 张迪 简秀华 |
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| 作者单位： | [1]贵州大学动物科学学院动物医学系,贵州贵阳550025 [2]北京航空航天大学生物工程系,北京100083 [3]贵阳市花溪农业局,贵州贵阳550025 |
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| 摘 要： | 紫苏具有良好的抗氧化作用，但大部分研究只局限于体外实验，有关调节血脂方面的研究则鲜有报道，并且研究主要是集中在紫苏籽油上。对于紫苏叶是否具有抗高脂血症及脂质过氧化方面的研究还未见报道。为此，笔者从已有的理论基础出发．对紫苏叶提取物调节血脂及抗脂质过氧化的方面作用进行研究。
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| 关 键 词： | 紫苏 高脂血症 血脂 脂质过氧化 |
The Effects of Folium Perillae Extract on Blood Fat and Lipid per Oxidation of Rabbit with Hyperlipemia |
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| TAN Jian-min,CHEN Juan-hua,XU Zai-pin,HUO Xin,DENG Xiao-yan,ZHANG Di,JIAN Xiu-hua.The Effects of Folium Perillae Extract on Blood Fat and Lipid per Oxidation of Rabbit with Hyperlipemia[J].Agricultural Science ＆ Technology,2008,9(1):121-124. |
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| Authors: | TAN Jian-min CHEN Juan-hua XU Zai-pin HUO Xin DENG Xiao-yan ZHANG Di JIAN Xiu-hua |
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| Institution: | TAN Jian-min, CHEN Juan-hua,XU Zai-pin, HUO Xin, DENG Xiao-yan,ZHANG Di,JIAN Xiu-hua (1. Department of Veterinary Medicine, College of Animal Science, Guizhou University, Guiyang 550025 ;2. Department of Bioengineering, Beijing University of Aeronautics ＆ Astronautics, Beijing 100083 ;3. Agricultural bureau of Huaxi District, Guiyang 550025) |
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| Abstract: | Objective]The preventive and therapeutic effects of Folium perillae extract(FPE)on hyperlipemia induced by feeding rabbit with high fat forage were observed.Method]The high fat and cholesterol diet were adopted to create the hyperlipemia model of rabbit.The rabbits were randomly and equally divided into 5 groups which were NC(normal control)group,HLM(high lipid model)group,LFPE,MFPE and HFPE group(low,middle,high dosage of FPE were 0.17 g/kg,0.5 g/kg and 1.5 g/kg respectively).The contents of TC(2,TG,LDL-C,HDL-C,MDA and the activity of SOD in serum were detected respectively.Result]The three FPE groups could decrease the contents of TC,TG,LDL-C,MDA significantly(P＜0.01 )compared with these of HLM group,and the contents of HDL-C(P＜0.01)) and the activity of SOD(P＜0.05) in serum was increased significantly.Conclusion]FPE could regulate blood-fat and counteraet lipid peroxidation. |
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| Keywords: | Folum perillae extract(FPE) Blood fat Malonaldehyde(MDA) Superoxide dismutase(SOD) |
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