| 壳聚糖基纤维止血效果研究(英文) |
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| 引用本文： | 高金伟,刘万顺,韩宝琴,周文丽.壳聚糖基纤维止血效果研究(英文)[J].农业科学与技术,2012(7):1555-1557. |
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| 作者姓名： | 高金伟 刘万顺 韩宝琴 周文丽 |
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| 作者单位： | 天津农学院水产科学系天津市水产生态及养殖重点实验室;中国海洋大学海洋生命学院225实验室 |
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| 摘 要： | 目的]探讨壳聚糖基纤维对肝脏的止血效果。方法]建立兔肝脏出血模型。试验组使用壳聚糖基纤维贴敷创面,对照组使用速即纱,空白组不使用任何材料。术后观察止血效果,记录各组的总出血量和止血率。结果]试验组在观察期无出血现象,止血率为100%,出血量为(0.443±0.030)g/kg,显著优于对照组和空白组(P<0.05)。结论]壳聚糖基纤维对肝脏创面止血效果显著,为进一步开展临床试验提供了依据。
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| 关 键 词： | 壳聚糖基纤维 止血 出血量 止血率 |
Hemostatic Effect of Chitosan-based Fiber |
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| Jinwei GAO,Wanshun LIU,Baoqin HAN,Wenli ZHOU.Hemostatic Effect of Chitosan-based Fiber[J].Agricultural Science ＆ Technology,2012(7):1555-1557. |
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| Authors: | Jinwei GAO Wanshun LIU Baoqin HAN Wenli ZHOU |
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| Institution: | 1. Tianjin Key Laboratory of Aqua-ecology and Aquaculture. Department of Fishery Science. Tianjin Agricultural University, Tianjin 300384, China; 2. 225 Laboratory, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China |
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| Abstract: | Objective] The aim was to investigate the hemostatic effects of chitosan-based fibre on liver. Method] The liver hemorrhage model of rabbit was established. Hemostasis was performed with chitosam-based fiber in experimental group, surgicel in control group and no material in blank group. The hemostatic effects were evaluated by total blood loss (TBL) and hemostatic rate. Result] Experimental group had no bleeding in observation period, with the hemostatic rate of 100% and the blood loss of only (0.443±0.30) g/kg, better than the control group and blank group (P<0.005). Conclusion] Chitosan-based fiber has effective hemostasis in liver wound, which will provide reliable information for the clinical trials. |
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| Keywords: | Chitosan-based fiber Hemostasis Blood loss Hemostatic rate |
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