| 高致病性猪繁殖与呼吸综合征病毒在自然病例组织中的定位 |
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| 引用本文： | 刘永宏,赵丽,韩春华,王凤龙,刘月焕,林健,杨汉春,郭鑫,李栋梁,韦海涛,祝俊杰,赵景义,赵振华,马明,杨龙峰,王金玲.高致病性猪繁殖与呼吸综合征病毒在自然病例组织中的定位[J].农业科学与技术,2009,10(2):20-25. |
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| 作者姓名： | 刘永宏 赵丽 韩春华 王凤龙 刘月焕 林健 杨汉春 郭鑫 李栋梁 韦海涛 祝俊杰 赵景义 赵振华 马明 杨龙峰 王金玲 |
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| 作者单位： | 刘永宏,赵丽,王凤龙,赵振华,王金玲,LIU Yong-hong,ZHAO Li,WANG Feng-long,ZHAO Zhen-hua,WANG Jin-ling(内蒙古农业大学动物科学与医学学院,内蒙古呼和浩特,010018);韩春华,刘月焕,林健,HAN Chun-hua,LIU Yue-huan,LIN Jian(北京市农林科学院畜牧兽医研究所,北京,100097);杨汉春,郭鑫,马明,YANG Han-chun,GUO Xin,MA Ming(中国农业大学动物医学院,北京,100094);李栋梁,韦海涛,祝俊杰,赵景义,LI Dong-liang,WEI Hai-tao,ZHU Jun-jie,ZHAO Jing-yi(北京市畜牧兽医总站,北京,100029);杨龙峰,YANG Long-feng(北京市延庆县动物卫生监督管理局,北京,102100)
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| 基金项目： | 北京市农林科学院青年基金，北京市科委猪高致病性蓝耳病防控技术子课题 |
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| 摘 要： | 猪繁殖与呼吸综合征（PRRS）是由猪繁殖与呼吸综合征病毒（PRRSV）引起，以怀孕母猪发生流产、早产和死胎等严重的繁殖障碍及仔猪和育肥猪发生呼吸道疾病为主要症状的传染病，是一种免疫抑制性疾病。猪感染PRRSV后的组织学病理变化主要集中在肺脏和淋巴结等器官；急性PRRS表现为败血症，全身性巨噬细胞和血管内皮细胞肿大、活化或增生，间质性肺炎，
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| 关 键 词： | 猪繁殖与呼吸综合征病毒 组织学 自然病例 高致病性 免疫抑制性疾病 PRRSV 定位 血管内皮细胞 |
Location of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in Tissues of Natural Cases |
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| LIU Yong-hong,ZHAO Li,HAN Chun-hua,WANG Feng-long,LIU Yue-huan,LIN Jian,YANG Han-chun,GUO Xin,LI Dong-liang,WEI Hai-tao,ZHU Jun-jie,ZHAO Jing-yi,ZHAO Zhen-hua,MA Ming,YANG Long-feng,WANG Jin-ling.Location of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in Tissues of Natural Cases[J].Agricultural Science ＆ Technology,2009,10(2):20-25. |
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| Authors: | LIU Yong-hong ZHAO Li HAN Chun-hua WANG Feng-long LIU Yue-huan LIN Jian YANG Han-chun GUO Xin LI Dong-liang WEI Hai-tao ZHU Jun-jie ZHAO Jing-yi ZHAO Zhen-hua MA Ming YANG Long-feng WANG Jin-ling |
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| Institution: | 1. College of Animal Science and Veterinary Medicine of Inner Mongolia Agricultural University, Hohhot 010018; 2. Institute of Animal Sci- ences, Chinese Academy of Agricultural Sciences, Beijing 100097; 3. College of Veterinary Medicine, China Agricultural University, Beijing 100094; 4. Animal Health Administration in Yanqing County of Beijing, Beijing 102100; 5. Animal Husbandry and Veterinary Station of Beijing, Beijing 100029) |
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| Abstract: | Objective] The aim of this study was to provide a theoretical basis for the prevention and treatment of highly pathogenic porcine reproductive and respiratory syndrome (HP-PRRS). Method] Antigen location and histopathological observation in natural cases infected by highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) were analyzed by immunohistochemistry and H.E. staining. Result] The virus antigen mainly existed in epithelial cells, and also a few in macrophages, lymphocytes and brain nerve cells. Conclusion] The cell and tissue tropism of HP-PRRSV strain in natural cases is different from that of previous strains. |
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| Keywords: | Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Natural case Immunohistochemistry Antigen location |
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