| 莲花烷类生物碱化学成分和药理活性研究进展 |
| |
| 引用本文： | 唐丽佳,何丽,关焕玉,张楠,张建新,刘建华,张援虎.莲花烷类生物碱化学成分和药理活性研究进展[J].贵州大学学报(农业与生物科学版),2014(5):81-85. |
| |
| 作者姓名： | 唐丽佳 何丽 关焕玉 张楠 张建新 刘建华 张援虎 |
| |
| 作者单位： | 贵州省中国科学院天然产物化学重点实验室,贵州贵阳550002 |
| |
| 基金项目： | 973计划前期研究专项项目课题（2012CB722601）;国家重大科学仪器设备开发专项项目（2011YQ12003506） |
| |
| 摘 要： | 莲花烷类生物碱属于异喹啉类吗啡型生物碱,主要存在于防己科千金藤属植物中,目前已发现70余个。其药理活性主要表现在抗HBV、与δ-阿片受体结合、抗单纯疱疹病毒等方面。为了更好地开发利用莲花烷类生物碱,本文综述了其化学成分与药理活性的研究进展。
|
| 关 键 词： | 莲花烷类生物碱 抗HBV活性 δ-阿片受体 抗单纯疱疹病毒 抗肿瘤 |
Research Progress in the Chemical Constituent and Pharmacological Activity of Hasubanan Al- kaloids |
| |
| TANG Li-jia,HE Li,GUAN Huan-yu,ZHANG Nan,ZHANG Jian-xin,LIU Jian-hua,ZHANG Yuan-hu.Research Progress in the Chemical Constituent and Pharmacological Activity of Hasubanan Al- kaloids[J].Journal of Mountain Agriculture & Biology,2014(5):81-85. |
| |
| Authors: | TANG Li-jia HE Li GUAN Huan-yu ZHANG Nan ZHANG Jian-xin LIU Jian-hua ZHANG Yuan-hu |
| |
| Institution: | ( The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang Guizhou 550002, China) |
| |
| Abstract: | The hasubanan alkaloids represent a group of naturally occurring isoquinolines morphine alkaloids which mainly found in plants from the genus Stephania （Menispermaceae）. Up to now, about seventy com- pounds of this family of natural products were obtained and their activities in anti - HBV, δ - opioid receptor binding, and anti herpes simplex virus were reported. Recent studies on the chemical constituent and phar- macological activity of hasubanan alkaloids were reviewed in this article for their future research and applica- tion. |
| |
| Keywords: | hasubanan alkaloids anti - HBV activity δ- opioid receptor anti herpes simplex virus anti-tumor activity |
| 本文献已被 CNKI 维普 等数据库收录！ |
