半乳糖对产蛋鹌鹑的卵巢毒性及牛磺酸的预防作用

将120只5月龄产蛋日本鹌鹑随机平均分成4组，进行两个阶段的试验。第一阶段各组鹌鹑在正常饲料中分别添加A.对照(不添加牛磺酸和半乳糖)；B.1%牛磺酸；C.10%半乳糖；D.10%半乳糖+1%牛磺酸；第二阶段各组鹌鹑在正常饲料中分别添加A.对照(不添加牛磺酸和半乳糖)；B.1%牛磺酸；C.5%半乳糖；D.5%半乳糖+1%牛磺酸。记录各组鹌鹑产蛋个数、重量、采食量和死亡率。结果显示与对照组和牛磺酸组相比，10%的半乳糖(C组和D组)使鹌鹑产蛋量和采食量都显著下降(P＜0.05)。半乳 糖处理9～10d后，C组鹌鹑几乎停止产蛋，且死亡率达 到20%，是其它3组(3.33%)的6倍多(P＜0.05)。牛磺 酸对半乳糖引起的产蛋量下降有一定的延迟作用，且D 组鹌鹑的产蛋量始终高于C组。在第二个阶段，当半乳 糖含量降至5%时，C组和D组鹌鹑的产蛋量及采食量都逐渐提高。D组鹌鹑产蛋量的恢复速度显著高于C组(P＜0.05)。在第二阶段试验结束时，D组鹌鹑的产蛋量和采食量几乎与A组和B组相等，这表明1%牛磺酸对5%半乳糖引起的卵巢毒性有很好的预防作用。

Ovarian Toxicity of Galactose to Egg-laying Quails and the Preventive Effects of Taurine

The ovarian toxicity of galactose and the preventive effects oftaurine on the toxicity induced by galactose in egg-laying Japanese quail were investigated．120 five-month-old egg laying Japanese quails were randomly and equally divided into four groups．In the first stage，the diets for four groups were added with：A．control（without taurine and galactose）；B.1％taurine；C.10％ galactose；D.10％ galactose＋1％ taurine.In the second stage，the diets were added with A.control （without taurine and galactose）；B.1％ taurine；C.5％ galactose；D.5％ galactose＋1％ taurine．Egg production including number and weight，food intake and mortality were recorded．Egg production （number and weight）and food intake were decreased strikingly after exposure to 10％ galactose．After 9～10 d of 10％ galactose treatment，the quails nearly stopped laying eggs and the death percentage increased to 20％ which was six times the rate of 3.33% in the other three groups（P＜0.05）．The total food intake at the first stage in group C was just half of that in group A and group B．1％ taurine had delayed onset of decreased egg production induced by 10％ galactose，and the egg production in group D remained higher than that in group C throughout．In the second stage，when galactose was decreased to 5％ in the diet，the egg production and food intake increased．Egg production in the group D recovered more rapidly than that in group C（P＜0.05)．At the end of the second stage，the egg production and food intake were nearly identical to those in group A and group B，showing that 1％ taurine was effective on preventing the toxicity induced by 5％ galactose．The data indicates：①Japanese quail is much sensitive to the toxicity of galactose，because galactose is not tolerated by quail when fed at 10 percent of the diet；②taurine is highly effective on preventing the ovarian toxicity of galactose；③further studies of the ovarian actions of galactose should take advantage of this novel animal model．