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哈维氏弧菌的血清型与菌苗抗原性的关系
引用本文:毛芝娟,楼丹,吴雄飞,楠田理一,陈昌福.哈维氏弧菌的血清型与菌苗抗原性的关系[J].华中农业大学学报,2003,22(6):588-590.
作者姓名:毛芝娟  楼丹  吴雄飞  楠田理一  陈昌福
作者单位:1. 宁波市水产研究所,宁波,315012
2. 日本国福山大学工学部海洋生物工学科,福山,729-02
3. 华中农业大学水产学院,武汉,430070;华中农业大学农业微生物国家重点实验室,武汉,430070
基金项目:宁波市青年科技基金项目(991104),国家自然科学基金项目(30271032)资助
摘    要:采用不同血清型哈维氏弧菌Vibrio hanwyi624、809和106等3个菌株,制备成福尔马林灭活菌苗,注射接种大黄鱼4周后,通过血清中凝集、交叉凝集抗体效价测定以及活菌攻毒试验,证明了3个菌株制备的菌苗抗原性存在差异。

关 键 词:哈维氏弧菌  血清型  菌苗抗原性  菌株培养  免疫原制备  注射接种  大黄鱼
修稿时间:2003年7月8日

Relationship between the Serotype of Vibrio harveyi and the Antigenicity of the Bacterins
Mao Zhijuan Lou Dan Wu Xiongfei Riichi Kusuda Chen Changfu.Relationship between the Serotype of Vibrio harveyi and the Antigenicity of the Bacterins[J].Journal of Huazhong Agricultural University,2003,22(6):588-590.
Authors:Mao Zhijuan Lou Dan Wu Xiongfei Riichi Kusuda Chen Changfu
Abstract:Formalin killed cells of Vibrio harveyi were prepared with three strains:Y624, Y809 and Y106, which represented different serotypes. The difference of the antigenicity among the bacterins prepared with these three strains was investigated by monitoring of agglutinating antibody titer. High agglutinating antibody titer was detecled againsl immunized antigen, but low cross-agglutinating anti-body liter was found. Challenge test with live pathogenic bacteria resulted in high survival percent a-gainst the corresponding one but low percent to the other two strains. It was suggested that the antigenicity of the bacterins prepared with the three strains was differenl.
Keywords:Vibrio harveyi  serotypes  antigenicity
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