| 微囊藻毒素对家兔部分血液生理生化指标的影响 |
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| 引用本文： | 张学振,李大鹏.微囊藻毒素对家兔部分血液生理生化指标的影响[J].华中农业大学学报,2009,28(2). |
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| 作者姓名： | 张学振 李大鹏 |
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| 作者单位： | 华中农业大学水产学院,武汉,430070 |
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| 摘 要： | 通过腹腔注射微囊藻毒素(microcystins,MCs)对家兔染毒,测定MC对家兔攻毒的LD50值,在不同时间点采样测定血液生理指标(红细胞计数、血红蛋白浓度、红细胞压积等)和血清酶(丙氨酸转氨酶、天门冬氨酸转氨酶、乳酸脱氢酶和碱性磷酸酶)活性变化.结果表明:家兔对微囊藻毒素较为敏感(对MC-LR的LD50为33μ/kg),血清酶活性变化灵敏,随着时间延长而逐渐升高,具有显著的时间效应关系,染毒动物在试验后期出现显著的正常红血球贫血病症.
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| 关 键 词： | 微囊藻毒素 家兔 血液 生理指标 生化指标 |
Effects of Microcystins on Some Physiological and Biochemical Parameters of Blood in Rabbit |
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| ZHANG Xue-zhen,LI Da-peng.Effects of Microcystins on Some Physiological and Biochemical Parameters of Blood in Rabbit[J].Journal of Huazhong Agricultural University,2009,28(2). |
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| Authors: | ZHANG Xue-zhen LI Da-peng |
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| Institution: | College of Fisheries;Huazhong Agricultural University;Wuhan 430070;China |
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| Abstract: | Rabbits were treated with intraperitoneally injection of microcystins(MCs),and LD50 value was determined.At different sampling points,blood physiological indices(including RBC,WBC,Hb and Ht) and serum enzymatic activities(including ALT,AST,LDH and ALP) were evaluated.The results indicated that rabbit was vulnerable to MC exposure,and activities of serum enzymes significantly increased with prolonged exposure time,exhibiting a significantly time-dependent effect.Blood physiological indices revealed that mark... |
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| Keywords: | microcystins rabbit blood physiological parameters biochemical parameters |
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