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水茄氯仿萃取物微乳剂配方的筛选
引用本文:桂王义,胡坚,董存柱,程晓莉,石坚,马瑞琪,方雨,蔡加挺,陈卜超.水茄氯仿萃取物微乳剂配方的筛选[J].贵州农业科学,2017,45(4).
作者姓名:桂王义  胡坚  董存柱  程晓莉  石坚  马瑞琪  方雨  蔡加挺  陈卜超
作者单位:海南大学热带农林学院,海南海口,570228
基金项目:海南省高等学校科学研究项目“水茄抑菌化合物追踪分离分析研究”
摘    要:为有效利用水茄资源,开发绿色环保并具有优良抑菌活性的水溶性农药应用于生产,通过对溶剂、乳化剂、水质及其量的筛选,确定水茄氯仿萃取物微乳剂初始配方;对pH、微乳液稳定性、低温稳定性、热贮稳定性、透明区域以及有效成分稳定性进行测定,确定其合格性。结果表明:二甲基亚砜对水茄提取物溶解效果最好,5g氯仿萃取物中加入20mL二甲基亚砜即可完全溶解并保持稳定;By-110为最佳乳化剂单体,每5g氯仿萃取物加入10g保证优良乳化性能;5%有效成分含量为水茄提取物微乳剂最佳有效成分含量;蒸馏水为最佳水质。该条件下制备的微乳剂剂型理化性状稳定,是一种合格的剂型。

关 键 词:水茄提取物  微乳剂  配方研制

Screening of Chloroform Extracts from Solanum torvum Micro-emulsion
GUI Wangyi,HU Jian,DONG Cunzhu,CHENG Xiaoli,SHI Jian,MA Ruiqi,FANG Yu,CAI Jiating,CHEN Buchao.Screening of Chloroform Extracts from Solanum torvum Micro-emulsion[J].Guizhou Agricultural Sciences,2017,45(4).
Authors:GUI Wangyi  HU Jian  DONG Cunzhu  CHENG Xiaoli  SHI Jian  MA Ruiqi  FANG Yu  CAI Jiating  CHEN Buchao
Abstract:In order to make full utilization of S.torvum resources,develop green environmental-friendly water-soluble pesticides with good antibacterial activity to use in production,After screening of solvens,emulsifiers,the type of waters,and the amount of every factors,the initiative microemulsifier formulation was determined.Through a series of performance testing,pH,the microemulsion stability,low temperature stability,thermal stability,transparent area,stability of active components,formulation was proved to be eligible.Results:Dimethyl sulfoxide was of the best dissolution effect,5 g chloroform extract was added with 20 mL solvent,By-110 monomer was the best emulsifier,Every 5 g chloroform extract was added to 10 g to ensure excellent emulsification,the best effective component content was 50;and the distilled water was the best choice.Through the performance test,the physical and chemical properties of this formulation were very stable.By various tests,Solanum torvum 5% micro-emulsion is a qualified formulation.
Keywords:extracts of Solanum torvum  micro-emulsion  formulation research
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