猪生长及胴体性状3个相关基因座遗传效应

 【目的】研究猪生长性状相关基因多态性，各多态位点对猪生长及胴体性状的影响，为分子标记辅助选择提供依据。【方法】采用PCR-RFLP方法分析PIT1、HDAC1、IGF2 基因在不同品种酶切位点多态性，分析不同基因型对生长与胴体性状的遗传效应。【结果】PIT1基因C等位基因、HDAC1基因G等位基因、IGF2基因A等位基因均有显著提高生长的效应，达100 kg活重所需时间一般可缩短6～9 d。PIT1基因C等位基因、HDAC1基因G等位基因、IGF2基因A等位基因提高瘦肉率3～5个百分点、背膘厚降低2～3 mm，生长性能指数得到相应提高。【结论】上述基因的有利等位基因有可能在选种中作为分子标记。

Genetic Effect of three Loci related with Growth and Carcass Traits in Swine

【Objective】 The objective of this study was to study the polymorphism of porcine three loci of PIT1, HDAC1 and IGF2 and its relationship with the growth and carcass traits in swine. 【Method】 The polymorphism of three genes was analyzed by PCR-RFLP method. The genotypic effects of such genes on growth and carcass traits were analyzed. 【Result】 CC genotype of PIT1, GG of HDAC1 and AA of IGF2 had favorable effect on growth and the age at 100 kg liveweight is 6-9days less than the contrary genotypes. The effects of CC genotype of PIT1, the GG genotype of HDAC1 and the BB genotype of IGF2 on lean percentage were 3-5 percent higher and on backfat thickness were 2-3 mm lower than the contrary genotypes. The index of growth traits increased relevantly.【Conclusion】 The favorable genotypes of thoese genes could be regarded as molecular markers in selection of lean type pigs.