| 黏蛋白在肠道寄生虫感染中的作用 |
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| 引用本文： | 苗雅娟,吴秀萍,王光明,王学林,赵颖.黏蛋白在肠道寄生虫感染中的作用[J].湖北农业科学,2012,51(12):2409-2411,2415. |
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| 作者姓名： | 苗雅娟 吴秀萍 王光明 王学林 赵颖 |
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| 作者单位： | 吉林大学人兽共患病研究所/人兽共患病教育部重点实验室,长春,130062 |
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| 摘 要： | 黏蛋白是由黏膜下腺体或上皮细胞中的黏液分泌的一种高分子蛋白,是一类具有典型黏附性和弹性的糖蛋白.在胃肠道寄生虫感染过程中,黏蛋白作为肠道黏膜屏障的主要组成部分在防御和清除寄生虫感染过程中发挥着重要作用.主要综述了黏蛋白的结构,糖基化模式以及感染个别肠道寄生虫时,相关的黏蛋白和黏蛋白样分子在宿主的先天性和适应免疫反应中所表现出的生化特性.
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| 关 键 词： | 黏蛋白 肠道寄生虫 黏蛋白样分子 |
Effect of Mucins on Intestinal Parasites Infection |
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| MIAO Ya-juan
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WU Xiu-ping
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WANG Guang-ming
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WANG Xue-lin
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ZHAO Ying.Effect of Mucins on Intestinal Parasites Infection[J].Hubei Agricultural Sciences,2012,51(12):2409-2411,2415. |
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| Authors: | MIAO Ya-juan WU Xiu-ping WANG Guang-ming WANG Xue-lin ZHAO Ying |
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| Institution: | (Institute of Zoonosis /Key Laboratory for Zoonosis Research,Ministry of Education,Jilin University,Changchun 130062,China) |
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| Abstract: | Mucin glycoproteins produced by mucus-producing cells in the epithelium or submucosal glands are macromolecular protein,which belong to a class of glycoproteins with typical adhesion and elasticity.During parasite infection,gastrointestinalas are major compartment of mucosal barrier.Mucins play an important role in the process of defense and clearance of parsite.The structure of mucin,glycosylation patterns and the biochemical properties of mucin and mucin-like olecule in relation to individual intestinal parasitic infection in the innate and adaptive immunity are reviewed. |
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| Keywords: | mucin intestinal parasites mucin-like molecule |
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