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| 甘氨胆酸抗炎作用的研究 | |
| 引用本文： | 李慧峰,李培锋,关红,李玉娟,王殿柱.甘氨胆酸抗炎作用的研究[J].内蒙古农业大学学报(自然科学版),2006,27(2):5-8. |
| 作者姓名： | 李慧峰 李培锋 关红 李玉娟 王殿柱 |
| 作者单位： | 1. 内蒙古农业大学动物科学与医学学院,呼和浩特,010018 2. 包头农牧学校,包头,014300 3. 包头市农垦集团,包头,014300 |
| 摘 要： | 目的:研究甘氨胆酸的抗炎作用。方法:采用小鼠耳廓肿胀法、皮内染料渗出法、甲醛和琼脂所致大鼠足跖肿胀法以及棉球肉芽肿胀法,观察甘氨胆酸的急慢性炎症反应。结果:高、低剂量的甘氨胆酸对二甲苯所致小鼠耳廓肿胀和小鼠皮肤毛细血管通透性,棉球所致小鼠肉芽肿,甲醛所致大鼠足跖肿胀以及琼脂所致大鼠足跖肿胀均有显著抑制作用。结论:甘氨胆酸对急性和慢性炎症均有显著的抑制作用。 |
| 关 键 词： | 胆汁 甘氨胆酸 抗炎作用 |
| 文章编号： | 1009-3575(2006)02-0005-04 |
| 收稿时间： | 2006-02-28 |
| 修稿时间： | 2006年2月28日 |
STUDIES ON ANTI- INFLAMMATION ACTIONS OF GLYCOCHOLIC ACID |
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| LI Hui-feng,LI Pei-feng,GUAN Hong,LI Yu-juan,WANG Dian-zhu.STUDIES ON ANTI- INFLAMMATION ACTIONS OF GLYCOCHOLIC ACID[J].Journal of Inner Mongolia Agricultural University(Natural Science Edition),2006,27(2):5-8. | |
| Authors: | LI Hui-feng LI Pei-feng GUAN Hong LI Yu-juan WANG Dian-zhu |
| Institution: | 1. College of Animal Science and Medicine,Inner Mongolia Agricultural University, Huhhot 010018 ,China; 2. Baotou Agricultural School,Baotou 014300;3. Baotou Land Reclamation Co. ,Ltd,Baotou 014300 |
| Abstract: | Anti-inflammatory actions of GCA was studied.The acute-inflammation was examined in rats whose auricles and intracutaneous suffered from xylene respectively and mice whose planters swelling was induced by formaldehyde and agar.The chronical-inflammation was examined in rats whose granuloma was induced by implanting cutton ball.GCA had significant effcts on the acute-inflammation and chronical-inflammation. |
| Keywords: | Glycocholic acid anti-inflammation |
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