昆虫CYP4基因家族多样性和进化

CYP4基因家族属于P450基因超家族中的一个基因家族。CYP4基因家族在昆虫中表现出极大的多样性,如亚家族及其成员的多样性、基因变异体、表达多样性等。所以,CYP4基因家族是研究进化的好材料。为了确定CYP4基因家族真正的进化机制,人们对它的内含子、外显子、氨基酸、假基因、镶嵌基因、启动子等其他功能片断进行过研究,但是不够深入。CYP4基因家族属于功能基因,所以,不仅要研究其核苷酸或者氨基酸序列,应该进一步研究其高级结构。

Insect Diversity and Its Evolution of the CYP4 Gene Family

CYP4 belongs to the P450 gene super family in a gene family.CYP4 family genes in insects are of great diversity,such as subfamily and its member diversity,gene variants,expression diversity etc,so the CYP4 gene family is a good material to study the evolution.To determine the true evolutionary mechanism of CYP4 gene family,people did a lot of study on CYP4 family genes evolutionary,such as CYP4 family gene intron sub,exon,amino acid,pseudogenes,mosaic gene,promoter and other functional fragments.But research in depth for this area is still necessary.As CYP4 family genes belong to the functional genes,not only further study is needed for nucleotide or amino acid sequences,but also for its senior structure.