| 鹿茸粉对四氯化碳急性肝损伤的保护作用 |
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| 引用本文： | 夏彦玲,李和平,宋伟杰.鹿茸粉对四氯化碳急性肝损伤的保护作用[J].东北林业大学学报,2009,37(7). |
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| 作者姓名： | 夏彦玲 李和平 宋伟杰 |
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| 作者单位： | 东北林业大学,哈尔滨,150040 |
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| 摘 要： | 利用四氯化碳构建小鼠急性肝损伤模型,测定小鼠血清中谷丙转氨酶(ALT)、谷草转氨酶(AST)活性,观察肝组织病理学形态,分析肝损伤程度.结果显示:鹿茸粉中、高剂量组与四氯化碳模型组相比ALT、AST水平显著降低(P<0.01),小剂量组差异不显著(P﹥0.05),中、高剂量组发生肝细胞坏死的动物例数减少,病变程度减轻.鹿茸粉对小鼠四氯化碳急性肝损伤有保护作用,且呈剂量依赖性.
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| 关 键 词： | 鹿茸粉 四氯化碳 肝损伤 |
Protective Effect of Antler Powder on Acute Hepatic Injury Induced by Carbon Tetrachloride |
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| Xia Yanling,Li Heping,Song Weijie.Protective Effect of Antler Powder on Acute Hepatic Injury Induced by Carbon Tetrachloride[J].Journal of Northeast Forestry University,2009,37(7). |
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| Authors: | Xia Yanling Li Heping Song Weijie |
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| Institution: | Xia Yanling,Li Heping,Song Weijie(College of Wildlife Resources,Northeast Forestry University,Harbin 150040,P. R. China) |
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| Abstract: | A model of acute hepatic injury induced by carbon tetrachloride (CCl4) was established using mice as experimental objects. Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) in serum were measured,and the pathological changes of liver tissue were also observed. Results showed that,compared with the CCl4 model group,the activities of ALT and AST decreased significantly in the middle and high dose groups of antler powder,and the number of animals with hepatocyte necrosis was lowered and the d... |
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| Keywords: | Antler powder Carbon tetrachloride Liver injury |
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