| 中药制剂“病毒宁”抗Ⅰ型单纯疱疹病毒的活性 |
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| 引用本文： | 吴国江,秦桂芳,李术娜,朱宝成.中药制剂“病毒宁”抗Ⅰ型单纯疱疹病毒的活性[J].河北农业大学学报,2007,30(4):59-62. |
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| 作者姓名： | 吴国江 秦桂芳 李术娜 朱宝成 |
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| 作者单位： | 1. 河北农业大学,生命科学学院,河北,保定,071001
2. 河北大学,卫生职业技术学院,河北,保定,071001 |
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| 摘 要： | 本试验研究了中药制剂“病毒宁”在体外对单纯疱疹病毒(HSV-1)增殖的抑制作用。结果显示:“病毒宁”在1.500~0.188 g/L稀释浓度下,对HSV-1有直接杀灭作用(P<0.05);“病毒宁”在1.500~0.375 g/L稀释浓度时,能显著阻断HSV-1对BKH-21细胞的感染(P<0.05),并显著抑制病毒在细胞内的增殖(P<0.05);中药制剂“病毒宁”在体外具有明显的抗HSV-1作用,其最大无毒浓度为1.500 g/L。
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| 关 键 词： | “病毒宁”制剂 抑制 疱疹病毒Ⅰ型 活性 |
| 文章编号： | 1000-1573(2007)04-0059-04 |
| 修稿时间： | 2006年12月28 |
The activity of the dosage 'bingduning' against HSV-1 in vitro |
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| WU Guo-jing,QIN Gui-fang,LI Shu-na,ZHU Bao-cheng.The activity of the dosage ''''bingduning'''' against HSV-1 in vitro[J].Journal of Agricultural University of Hebei,2007,30(4):59-62. |
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| Authors: | WU Guo-jing QIN Gui-fang LI Shu-na ZHU Bao-cheng |
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| Abstract: | In this research,the HSV-1 was treated with 'bingduning' at different conditions,and 'bingduning's activity against HSV-1 in vitro was determined.The result showed that 'bingduning' can obviously kill HSV-1 at the diluted concentration of 1.500～0.188 g/L;at the concentration of 1.500～0.375 g/L,'bingduning' can prevent the infection of HSV-1 to the BKH-21 cells(P<0.05)and inhibit the HSV-1's duplication in BKH-21 cells remarkably.bingduning has anti-activity to HSV-1 in vitro,and the max avirulence concentration is 1.500 g/L. |
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| Keywords: | 'bingduning' dosage inhibotry HSV-1 activity |
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