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| 苦参碱纳米乳的研制及其对小鼠抗氧化作用的影响 | |
| 引用本文： | 曹发昊,欧阳五庆,王艳萍.苦参碱纳米乳的研制及其对小鼠抗氧化作用的影响[J].西北农林科技大学学报(社会科学版),2007,35(3):61-64. |
| 作者姓名： | 曹发昊 欧阳五庆 王艳萍 |
| 作者单位： | 1. 西北农林科技大学,动物科技学院,陕西,杨凌,712100;西北农林科技大学,国家生命科学与技术人才培养基地,陕西,杨凌,712100 2. 西北农林科技大学,动物科技学院,陕西,杨凌,712100 3. 河南农业大学,食品科学与技术学院,河南,郑州,450002 |
| 摘 要： | 以肉豆蔻酸异丙脂、聚氧乙烯醚-40氢化蓖麻油(Cremorphor RH40)、苦参碱和蒸馏水为原料,研制苦参碱纳米乳,检测其基本性质(形态、粒径分布、苦参碱含量及稳定性),并探讨了其对小鼠血清和肝组织中丙二醛含量和超氧化物歧化酶活性的影响。结果显示,苦参碱纳米乳为O/W型澄清透明液体,透射电镜下为球形液滴,平均粒径为70 nm,稳定性良好,苦参碱含量为110.12 mg/mL;苦参碱纳米乳可显著提高小鼠血清和肝组织的SOD活性(P<0.05),降低MDA含量(P<0.05)。苦参碱纳米乳质量稳定,能提高小鼠的抗氧化能力。 |
| 关 键 词： | 苦参碱 纳米乳 抗氧化 丙二醛 超氧化物歧化酶 聚氧乙烯醚-40氢化蓖麻油 |
| 文章编号： | 1671-9387(2007)03-0061-04 |
| 收稿时间： | 2006/8/31 0:00:00 |
| 修稿时间： | 2006-08-31 |
Study of preparation of matrin nanoemulsion and its anti-oxidation on mice |
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| CAO Fa-hao,OUYANG Wu-qing,WANG Yan-ping,DONG Hong-bin.Study of preparation of matrin nanoemulsion and its anti-oxidation on mice[J].Journal of Northwest Sci-Tech Univ of Agr and,2007,35(3):61-64. | |
| Authors: | CAO Fa-hao OUYANG Wu-qing WANG Yan-ping DONG Hong-bin |
| Institution: | 1,2(1 College of Annimal Science and Technology,Northwest A & F University,Yangling,Shaanxi 712100,China;2 The National Base of Life Science and Biotechnology Education,Northwest A & F University,Yangling,Shaanxi 712100,China;3 College of Food Science and Technology,He’nan Agriculture University,Zhengzhou,He’nan 450002,China) |
| Abstract: | The matrin nanoemulsion was produced with IPM,matrin,Cremorphor RH40 and distilled water,and its morphology,particle size distribution,matrin content and stability were evaluated,and its effects on MDA and SOD in blood and liver tissue of mice were studied.The results showed that the matrin nanoemulsion whose type was oil-in-water was stable and its average diameter was about 70 nm.The content of matrin in nanoemulsion was 110.12 mg/mL.Compared with control groups,the activity of SOD in matrin nanoemulsion groups significantly increased(P<0.05),yet the content of MDA decreased(P<0.05).The matrin nanoemulsion is a suitable preparation with better stability and anti-oxidation effect. |
| Keywords: | matrin nanoemulsion MDA SOD Cremorphor RH40 |
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