| 调环酸钙安全性初步评价 |
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| 引用本文： | 郑先福,赵东生,孙炳剑,郑昊.调环酸钙安全性初步评价[J].广西农业科学,2011,42(3):288-290. |
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| 作者姓名： | 郑先福 赵东生 孙炳剑 郑昊 |
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| 作者单位： | 1. 河南农业大学
2. 郑州郑氏化工产品有限公司,郑州,450002 |
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| 基金项目： | 河南省重大科技攻关计划项目 |
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| 摘 要： | 【目的】评价调环酸钙原药的急性毒性,为安全使用调环酸钙提供毒理学依据。【方法】按照我国现行《农药登记毒理学试验方法》（GB15670-1995）规定的方法,以SD大鼠为对象,采用一次最大剂量法,对调环酸钙原药进行急性经口、经皮毒性试验。【结果】调环酸钙原药对SD大鼠的急性经口半数致死量（LD50）〉5000mg/kg·BW,经皮LD50〉2000mg/kg·BW。【结论】调环酸钙对大鼠的急性经口、经皮毒性均属于低毒性,符合绿色农业生产的要求。
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| 关 键 词： | 调环酸钙 植物生长调节剂 急性毒性 安全评价 |
Preliminary evaluation on the security of prohexadione-calcium |
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| ZHENG Xian-fu,ZHAO Dong-sheng,SUN Bing-jian,ZHENG Hao.Preliminary evaluation on the security of prohexadione-calcium[J].Guangxi Agricultural Sciences,2011,42(3):288-290. |
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| Authors: | ZHENG Xian-fu ZHAO Dong-sheng SUN Bing-jian ZHENG Hao |
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| Institution: | ZHENG Xian-fu, ZHAO Dong-sheng, SUN Bing-jian, ZHENG Hao (1 Henan Agricultural University, Zhengzhou 450002, China; 2 Zhengzhou Zhengshi Chemical Co., Ltd., Zhengzhou 450002, China) |
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| Abstract: | 【Objective】The objective of the present study was to test the acute toxicity of the raw pesticides of prohexadione-calcium, and to provide toxicological basis for using proexhadione calcium safely. 【Method】The tests of acute oral and percutaneous toxicity were undertaken based on the Chinese standards （GB 15670-1995） of Toxicological Test Methods of Pesticides for Registration. 【Result】The acute oral toxicity LD50 of proexhadione calcium on SD rats was over 5000 mg/kg·BW, and the percutaneous toxicity was over 2000 mg/kg·BW. 【Conclusion】The acute oral, percutaneous toxicity of percutaneous toxicity on rats is low, which is safe for human beings and domestic animals. |
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| Keywords: | Prohexadion-calcium plant growth regulator acute toxicity safety evaluation |
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