| 核酸适配体技术在食品有害物检测中的研究进展 |
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| 引用本文： | 卢军利,葛玮东,孙建霞,杨勇,焦睿,欧仕益,白卫滨.核酸适配体技术在食品有害物检测中的研究进展[J].中国农业科技导报,2015,17(2):151-158. |
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| 作者姓名： | 卢军利 葛玮东 孙建霞 杨勇 焦睿 欧仕益 白卫滨 |
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| 作者单位： | （1.暨南大学食品科学与工程系, 广州 510632,2.四川农业大学食品学院, 四川 雅安 625014,3.伊梨州妇幼保健院, 新疆 伊宁 835000,4.广东工业大学轻工化工学院, 广州 510090) |
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| 基金项目： | “十二五”国家科技支撑计划项目(2012BAD36B04);广东高校优秀青年创新人才培育项目(LYM10033)资助 |
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| 摘 要： | 核酸适配体是一段可以特异性识别并结合靶分子的寡聚核苷酸片段,具有亲和力强、稳定性好、易于修饰等特点,已经广泛用于检测、分离纯化和医疗三大领域。基于核酸适配体技术的检测方法得到了迅速地发展,已经应用于小分子、蛋白质、细菌病毒等方面的检测。主要综述了核酸适配体检测食品中有害物的研究进展。
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| 关 键 词： | 核酸适配体 检测 食品 有害物 |
Research Progress of Aptamer in Detecting Harmful Substances in Food |
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| LU Jun-li;GE Wei-dong;SUN Jian-xia;YANG Yong;JIAO Rui;OU Shi-yi;BAI Wei-bin.Research Progress of Aptamer in Detecting Harmful Substances in Food[J].Journal of Agricultural Science and Technology,2015,17(2):151-158. |
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| Authors: | LU Jun-li;GE Wei-dong;SUN Jian-xia;YANG Yong;JIAO Rui;OU Shi-yi;BAI Wei-bin |
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| Institution: | (1.Department of Food Science and Engineering, Jinan University, Guangzhou 510632|2.College of Food Science, Sichuan Agricultural University, Sichuan Yaan 625014|3.Yili Maternal and Child Health Care Hospital, Xinjiang Yining 835000|4.Faculty of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, China) |
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| Abstract: | Aptamer is an oligonucleotide that can recognize specificity and bind to corresponding targets. It has strong affinity and is highly stable and easier to modify. It has been widely used in detection, separation and purification, medical treatment. The detection assay based on nucleic acid aptamer technology has developed rapidly, and been applied in detecting small molecule, protein, bacteria and viruses, etc.. This paper reviewed the research progress in detecting harmful substances in food by nucleic acid aptamer. |
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| Keywords: | nucleic acid aptamer detection food harmful substances |
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