首页 | 本学科首页   官方微博 | 高级检索  
     检索      

以鹿茸为模型探索软骨组织发生
引用本文:路晓,孙红梅,张伟,李春义.以鹿茸为模型探索软骨组织发生[J].中国农业科技导报,2015,17(4):71-77.
作者姓名:路晓  孙红梅  张伟  李春义
作者单位:(中国农业科学院特产研究所, 特种经济动物分子生物学国家重点实验室, 长春 130000)
基金项目:国家863计划项目(2011AA100603);国家自然科学基金项目(31170950)资助。
摘    要:软骨组织的研究一直依赖于哺乳动物胚胎模型,这种方法存在取材困难、难以明确界定分层边界等弊端。而鹿茸非常独特,可以作为一种新的生物医学模型对软骨发育进行研究。通过比较传统的软骨研究模型和鹿茸这种新型模型,分析了鹿茸作为软骨研究模型的优势,同时对鹿茸软骨组织发生与生长的组织基础,以及分子调控机制的研究进展进行了综述,并对鹿茸软骨组织中血管生成的调控因子进行了探讨,以期为寻找更有效的软骨发育研究模型提供理论参考。

关 键 词:鹿茸  软骨发生  调控机制  
收稿时间:2015-02-02

Exploration of Cartilage Development Using Deer Antler Model
LU Xiao,SUN Hong-mei,ZHANG Wei,LI Chun-yi.Exploration of Cartilage Development Using Deer Antler Model[J].Journal of Agricultural Science and Technology,2015,17(4):71-77.
Authors:LU Xiao  SUN Hong-mei  ZHANG Wei  LI Chun-yi
Institution:(State Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Animal and Plant Sciences, Chinese Acadmy of Agricultural Sciences, Changchun 130000, China)
Abstract:Studies on cartilage tissues has been relying on embryo model of mammals. This method has difficulties in obtaining material and clearly defining layered boundaries. While, the antler is unique that can be used as a new biomedicine model to study cartilage development. Through comparing the traditional cartilage research model with the new antler model, this paper analyzed the advantages of antlers being a new cartilage research model; reviewed the turning up of antler cartilage and tissue foundation of its growth, and molecular regulation mechanism; discussed the regulatory factors in angiogenesis of antler cartilage, so as to provide theoretical basis for finding a more effective model in studying cartilage development.
Keywords:antler  chondrogenesis  regulation mechanism  
本文献已被 CNKI 等数据库收录!
点击此处可从《中国农业科技导报》浏览原始摘要信息
点击此处可从《中国农业科技导报》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号