| 担子菌中甲羟戊酸途径影响萜类物质合成的研究 |
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| 引用本文： | 李亮,尚晓冬,谭琦.担子菌中甲羟戊酸途径影响萜类物质合成的研究[J].中国农业科技导报,2014,16(3):53-61. |
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| 作者姓名： | 李亮 尚晓冬 谭琦 |
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| 作者单位： | (1.上海市农业科学院食用菌研究所, 国家食用菌工程技术研究中心,
农业部应用真菌资源与利用重点开放实验室, 上海市农业遗传育种重点实验室, 上海 201106,
2.上海海洋大学食品科学学院, 上海 200090) |
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| 基金项目： | 国家“十二五”科技支撑项目(2013BAD16B02)；上海市科技人才计划项目（13XD1424700）;上海科技兴农重点攻关项目\[沪农科攻字（2009）第2\|2号\]资助。 |
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| 摘 要： | 担子菌中具有多种萜类活性物质，这些活性物质对人类的营养和健康有着很重要的影响。甲羟戊酸途径是担子菌合成萜类物质的一条主要途径，萜类物质的含量水平受到甲羟戊酸途径的控制，但是生物细胞内萜类物质的产量很低，并且目前活性萜类物质的化学以及生物合成方法效率低、成本高，因此为了能够更好的增加萜类物质在担子菌细胞内的产量，介绍了担子菌甲羟戊酸途径中乙酰辅酶A、HMG\|CoA、甲羟戊酸激酶影响萜类物质的合成作用，旨在通过调控这些物质来增加目标萜类物质的产量。
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| 关 键 词： | 担子菌 甲羟戊酸途径 萜类物质 |
| 收稿时间： | 2013-10-13 |
Studies|of Mevalonate Pathway Influence on Biosynthesis of Terpenoids in Basidiomycota |
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| LI Liang,SHANG Xiao\|dong,TAN Qi.Studies|of Mevalonate Pathway Influence on Biosynthesis of Terpenoids in Basidiomycota[J].Journal of Agricultural Science and Technology,2014,16(3):53-61. |
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| Authors: | LI Liang SHANG Xiao\|dong TAN Qi |
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| Institution: | (1.National Engineering Research Center of Edible Fungi, Key Laboratory of Applied Mycological Resources and Utilization, ;
Ministry of Agriculture|Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, ;
Shanghai Academy of Agricultural Sciences, Shanghai 201106|2.College of Food Science, Shanghai Ocean University, ;
Shanghai 200090, China) |
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| Abstract: | There are numerous active terpenoids in Basidiomycota cellular. These active substances have important influence on human nutrition and health. Mevalonate pathway, which can govern biosynthesis of some kinds of terpenoids, is an essential path in regulating secondary metabolism in Basidiomycota cells. However, the production of terpenoids in the cell is very low, and the chemical and biological synthesis methods of active terpenoids are with low efficiency and high cost. Therefore, in order to increase the output of terpenoids substances, this paper introduced some key substances, Acetyl\|CoA, HMG\|CoA, MVK, and their influences on biosynthesis of terpenoids, aiming at improving target terpenoids production by adjusting and controlling these substances. |
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| Keywords: | Basidiomycota mevalonate pathway terpenoids |
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