| RNA干扰技术应用的研究进展 |
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| 引用本文： | 王猛,马艳平,陈豪泰,马丽娜,丁耀忠,杨生海,刘永生,张杰.RNA干扰技术应用的研究进展[J].江西农业学报,2009,21(6):108-111. |
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| 作者姓名： | 王猛 马艳平 陈豪泰 马丽娜 丁耀忠 杨生海 刘永生 张杰 |
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| 作者单位： | 中国农业科学院,兰州兽医研究所,家畜疫病病原生物学国家重点实验室、农业部畜禽病毒学重点开放实验室、农业部兽医公共卫生重点开放实验室,甘肃,兰州,730046 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 综述了RNA干扰(RNAi)的作用机理、介导载体、在哺乳动物中的应用现状和前景。
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| 关 键 词： | RNA干扰 基因沉默 作用机理 介导载体 应用 |
Research Advances in Application of RNA Interference Technique |
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| WANG Meng,MA Yan-ping,CHEN Hao-tai,MA Li-na,DING Yao-zhong,YANG Sheng-hai,LIU Yong-sheng,ZHANG Jie.Research Advances in Application of RNA Interference Technique[J].Acta Agriculturae Jiangxi,2009,21(6):108-111. |
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| Authors: | WANG Meng MA Yan-ping CHEN Hao-tai MA Li-na DING Yao-zhong YANG Sheng-hai LIU Yong-sheng ZHANG Jie |
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| Institution: | State Key Laboratory of Veterinary Etiological Biology;Key Laboratory of Animal Virology of Ministry of Agriculture;Key Laboratory of Veterinary Public Health of Ministry of Agriculture;Lanzhou Veterinary Research Institute;Chinese Academy of Agricultural Sciences;Lanzhou 730046;China |
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| Abstract: | RNA interference(RNAi) refers to high-efficient and specific degradation phenomenon of homologous mRNA induced by double-stranded RNA in the highly conserved evolutionary course.RNAi technology has rapidly developed in the biomedicine research,it has played an important role in identifying unknown genes,tumour,antiviral infection and so on.This thesis sums up the action mechanism of RNAi,the carrier,the application situation and the prospects in mammal. |
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| Keywords: | RNAi Gene silence Mechanism Mediated vector Application |
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