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CO2超临界和乙醇提取蜂胶对大鼠降血脂效果
引用本文:曾志将,杨明,杨新跃,周银平,刘志勇.CO2超临界和乙醇提取蜂胶对大鼠降血脂效果[J].江西农业大学学报,2006,28(3):433-435.
作者姓名:曾志将  杨明  杨新跃  周银平  刘志勇
作者单位:1. 江西农业大学,动物科技学院,江西,南昌,330045
2. 江西省劳动卫生职业防治研究所,江西,南昌,330006
基金项目:江西省农业厅资助项目(赣农字〔2004〕84号)
摘    要:试验用健康雄性SD大鼠,给予高脂颗粒饲料喂饲后第9 d,大鼠眶静脉取血,测定血清总胆固醇(TC)、甘油三酯(TG)和高密度脂蛋白(HDL-C)值。高脂血症动物模型成功后,随机分为对照组1(给予聚乙二醇400)、超临界蜂胶高剂量组(600 mg/kg BW)、超临界蜂胶中剂量组(300 mg/kg BW)、超临界蜂胶低剂量组(150 mg/kg BW);对照组2(给予食用油)、乙醇提取蜂胶高剂量组(600 mg/kg BW)、乙醇提取蜂胶中剂量组(300 mg/kg BW)、乙醇提取蜂胶低剂量组(150 mg/kg BW)8个组。分组后连续4周蜂胶灌胃,同时各组大鼠继续给予高脂颗粒饲料喂饲,之后各组大鼠取血测定TC、TG和HDL-C。结果表明:喂蜂胶28 d后,只有超临界蜂胶高剂量组(600 mg/kg BW)的TG值和乙醇提取蜂胶高剂量组(600 mg/kg BW)的TC值分别与相对照组差异显著,其它指标都差异不显著。

关 键 词:蜂胶  CO2超临界提取  乙醇提取  降血脂
文章编号:1000-2286(2006)03-0433-03
收稿时间:2005-11-28
修稿时间:2005年11月28

The Effect of Propolis Obtained by CO2 Supercritical Extraction and Ethanol Extraction on Decrease Lipoidemia
ZENG Zhi-jiang,YANG Ming,YANG Xin-yue,ZHOU Yin-ping,LIU Zhi-yong.The Effect of Propolis Obtained by CO2 Supercritical Extraction and Ethanol Extraction on Decrease Lipoidemia[J].Acta Agriculturae Universitis Jiangxiensis,2006,28(3):433-435.
Authors:ZENG Zhi-jiang  YANG Ming  YANG Xin-yue  ZHOU Yin-ping  LIU Zhi-yong
Institution:1. College of Animal Science and Technology, JAU, Nanchang 330045, China;2. Working Sanitation and Profession Prevention Institute of Jiangxi Province, Nanchang 330006,China
Abstract:Healthy male SD rats were fed with high-lipid pellet feed for 9 days,then blood from eyepit vein was collected to detect the levels of serum TC,TG and HDL-C.The rats were randomized into 8 groups.Different feeds for each group were arranged as follows:the supercritical proplis groups included the control group 1(without propolis),the high dose group(600 mg/kg BW),the middle dose group(300 mg/kg BW) and the low dose group(150 mg/kg BW).The alcohol proplis groups included the control group 2(without propolis),the high dose group(600 mg/kg BW),the middle dose group(300 mg/kg BW) and the low dose group(150 mg/kg BW).Then they were fed with propolis and high-lipid pellet feed in the meantime for 4 weeks.The blood was collected on the 28th day after fed with propolis and the levels of serum TC,TG and HDL-C were detected.The result showed that the effect of high dose supercritical propolis(600 mg/kg BW)on decreasing the content of serum TG and that of high dose alcohol propolis(600 mg/kg BW)on decreasing the content of serum TC in rats were significant,compared with the control groups respectively,but the other indexes were not.
Keywords:propolis  CO_2 supercritical extraction  ethanol extraction  decrease of lipoidemia
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