| 海带岩藻黄素对小鼠脂质过氧化抑制作用的影响 |
| |
| 引用本文： | 吴超,任丹丹,陈倩,汪秋宽.海带岩藻黄素对小鼠脂质过氧化抑制作用的影响[J].大连水产学院学报,2011,26(5):428-431. |
| |
| 作者姓名： | 吴超 任丹丹 陈倩 汪秋宽 |
| |
| 作者单位： | 大连海洋大学辽宁省水产品加工及综合利用重点开放实验室,辽宁大连,116023 |
| |
| 基金项目： | 辽宁省教育厅高等学校科研计划项目 |
| |
| 摘 要： | 用硫代巴比妥酸法测定小鼠肝组织及线粒体中丙二醛的含量,用分光光度法测定小鼠红细胞溶血和肝线粒体的肿胀程度,从而考察海带Laminaria japonica岩藻黄素对小鼠脂质体系的抗氧化能力。结果表明：岩藻黄素能在自发和诱导条件下抑制肝匀浆液及线粒体中丙二醛的产生,降低红细胞的溶血程度,并能减轻肝线粒体的肿胀程度,且其抑制作用均呈明显的剂量效应关系。这说明海带岩藻黄素具有明显的抗氧化作用。
|
| 关 键 词： | 海带 岩藻黄素 小鼠 抗氧化 |
Anti-lipid peroxidation effect of fucoxanthin from kelp Laminaria japonica in mice in vitro |
| |
| WU Chao,REN Dan-dan,CHEN Qian,WANG Qiu-kuan.Anti-lipid peroxidation effect of fucoxanthin from kelp Laminaria japonica in mice in vitro[J].Journal of Dalian Fisheries University,2011,26(5):428-431. |
| |
| Authors: | WU Chao REN Dan-dan CHEN Qian WANG Qiu-kuan |
| |
| Institution: | (The Key and Open Laboratory of Fishery Product Processing and Utilization of Liaoning Province,Dalian Ocean University,Dalian 116023,China) |
| |
| Abstract: | The contents of MDA in liver and liver mitochondria were studied by TBA assay in vitro,and the hemolysis extent of red blood cells and the swelling extent of liver mitochondria were detected by spectrophotometric method to evaluate the antioxidative effects of fucoxanthin from kelp Laminaria japonica in a lipid system of mice.The results showed that the fucoxanthin could inhibited the generation of MDA in liver and liver mitochondria under spontaneous or induced conditions.The swelling of liver mitochondria and the hemolysis of red blood cells were also inhibited with dose-response relationship,indicating that the fucoxanthin from the kelp had significant antioxidant activity. |
| |
| Keywords: | Laminaria japonica fucoxanthin mice antioxidation |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
