| 西洋参总皂苷及单体皂苷对胰脂肪酶活性的影响 |
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| 引用本文： | 张晶,郑毅男,李向高,韩立坤.西洋参总皂苷及单体皂苷对胰脂肪酶活性的影响[J].吉林农业大学学报,2002,24(1):62-63,87. |
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| 作者姓名： | 张晶 郑毅男 李向高 韩立坤 |
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| 作者单位： | 1. 吉林农业大学中药材学院,吉林,长春,130118
2. 日本爱媛大学医学部, 松山市791-0 2 |
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| 摘 要： | 首次对西洋参部皂苷及各单体皂进行了降脂活性的研究。结果表明：西洋参总皂苷较人参总皂苷对体外胰脂肪酶活性的抑制作用强，在0．5mg/mL浓度时抑率分别为90％和35．2％；人参皂苷Rc,Rb1,Rb2对胰脂肪酶少性均有很强的抑制作用，在0．5mg/mL浓度时抑制率分别为100％、96％、97％、初步揭示出它们具有被开发为降血脂新药的良好前景。
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| 关 键 词： | 西洋参 人参皂苷 胰脂肪酶 总皂苷 单体皂苷 活性影响 中药 |
| 文章编号： | 1000-5684(2002)01-0062-02 |
Effects of Saponins from Panax quinquefolium Linne on the Metabolism of Lipid |
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| ZHANG Jing ,ZHENG Yi nan ,LI Xiang gao ,HAN Li kun.Effects of Saponins from Panax quinquefolium Linne on the Metabolism of Lipid[J].Journal of Jilin Agricultural University,2002,24(1):62-63,87. |
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| Authors: | ZHANG Jing ZHENG Yi nan LI Xiang gao HAN Li kun |
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| Institution: | ZHANG Jing 1,ZHENG Yi nan 1,LI Xiang gao 1,HAN Li kun 2 |
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| Abstract: | Effects of saponins and monomer saponins from Panax quinquefolium Linne on the metabolism of lipid were studied The results showed that at the concentrations of 0 5 mg/mL, saponins inhibited the activity of pancreatic lipase by 90% and 35 2% respectively for American ginseng and ginseng At the concentrations of 0 5 mg/mL, ginsenosides of Rc, Rb 1 and Rb 2 inhibited the activity of pancreatic lipase by 100%, 96% and 97% respectively, showing that Rc could completely inhibit the activity of pancreatic lipase. These results indicated the potentials of saponins to be developed as new drugs of anti obesity |
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| Keywords: | Panax quinquefolium Linne saponin metabolism of lipid |
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