| 白鲢骨骼肌丝氨酸蛋白酶抑制剂对Jarkat,Sp20,MG63细胞增殖的影响 |
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| 引用本文： | 胡新颖,戴钟铨,马长伟,李莹辉.白鲢骨骼肌丝氨酸蛋白酶抑制剂对Jarkat,Sp20,MG63细胞增殖的影响[J].吉林农业大学学报,2006,28(1):32-34. |
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| 作者姓名： | 胡新颖 戴钟铨 马长伟 李莹辉 |
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| 作者单位： | 1. 中国农业大学食品科学与营养工程学院,北京,100083
2. 航天医学工程研究所,北京,100094 |
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| 基金项目： | 国家自然科学基金资助项目(30371122) |
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| 摘 要： | 应用MTT法分析了白鲢骨骼肌丝氨酸蛋白酶抑制剂对急性T细胞白血病细胞Jarkat、人骨髓瘤细胞Sp20和人骨瘤细胞MG63生长的影响。结果表明:白鲢骨骼肌丝氨酸蛋白酶抑制剂对以上3种肿瘤细胞的增殖都有抑制作用,而且抑制作用呈剂量依赖性;该丝氨酸蛋白酶抑制剂在0.1 g/L浓度下对Jarkat细胞的增殖有明显的抑制作用。
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| 关 键 词： | 白鲢 丝氨酸蛋白酶抑制剂 Jarkat细胞 Sp20细胞 MG63细胞 |
| 文章编号： | 1000-5684（2006）01-0032-03 |
| 收稿时间： | 2005-03-10 |
| 修稿时间： | 2005-03-10 |
Antiproliferative Effects of Serine Proteinase Inhibitor from Silver Carp( Hypophthalmichthys molitrix )Skeletal Muscle on Jarkat, Sp20 and MG63 Cells |
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| HU Xin-ying,DAI Zhong-quan,MA Chang-wei,LI Ying-hui.Antiproliferative Effects of Serine Proteinase Inhibitor from Silver Carp( Hypophthalmichthys molitrix )Skeletal Muscle on Jarkat, Sp20 and MG63 Cells[J].Journal of Jilin Agricultural University,2006,28(1):32-34. |
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| Authors: | HU Xin-ying DAI Zhong-quan MA Chang-wei LI Ying-hui |
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| Institution: | 1. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China; 2. Institute of Space Medico-Engineering, Beijing 100094, China |
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| Abstract: | The antiproliferative effects of the purified serine proteinase inhibitor were determined by MTT on Sp20,Jarkat and MG63 cells.The results showed serine proteinase inhibitor from silver carp skeletal muscle inhibited the proliferation of the above three types of cells in a dose-dependent manner and among which concentration of 0.1 g/L serine proteinase inhibitor had an effect on Jarkat cells. |
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| Keywords: | silver carp serine proteinase inhibitor Jarkat cell Sp20 cell MG63 cell |
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