| 哺乳仔猪外周血5-羟色胺的合成与代谢研究 |
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| 引用本文： | 张晗,张涛,王磊,张爽,王安如,滕可导.哺乳仔猪外周血5-羟色胺的合成与代谢研究[J].安徽农业科学,2010,38(5):2381-2383. |
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| 作者姓名： | 张晗 张涛 王磊 张爽 王安如 滕可导 |
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| 作者单位： | 河北大学生命科学学院,河北保定,071002;北京农学院兽医学,中医药,北京市重点实验室,北京,102206;中国农业大学动物医学院,北京,100193 |
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| 基金项目： | “十一五”国家科技支撑计划项目(2007BAD86B-06) |
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| 摘 要： | 目的]探讨哺乳仔猪外周血5-羟色胺的合成与代谢随日龄变化的规律。方法]选用15只0、5和15日龄的英系大白猪为试验动物,采用反相高效液相色谱——紫外检测法对其外周血血清中L-Trp、5-HT和5-HIAA的含量进行测定。结果]仔猪初生时L-Trp的含量为（16.92±1.74）μmol/L,5日龄时为（59.94±10.88）μmol/L,15日龄时为（70.42±6.48）μmol/L;仔猪初生时5-HT的含量为（12.85±1.79）μmol/L,5日龄时为（4.81±2.05）μmol/L,15日龄时为（5.49±1.09）μmol/L;代谢产物5-HIAA在各日龄仔猪血清中均未检出。结论]随日龄增加,哺乳仔猪外周血L-Trp的含量显著增加（P〈0.05）,而5-HT的含量与L-Trp-5-HT通路转化率在初生时最高（P〈0.05）,此后趋于稳定（P〉0.05）。
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| 关 键 词： | 5-羟色胺 L-色氨酸 5-羟吲哚乙酸 外周血 哺乳仔猪 |
Synthesis and Metabolism of 5-hydroxytryptamine in Peripheral Circulatory System of Suckling Piglets |
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| ZHANG Han et al.Synthesis and Metabolism of 5-hydroxytryptamine in Peripheral Circulatory System of Suckling Piglets[J].Journal of Anhui Agricultural Sciences,2010,38(5):2381-2383. |
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| Authors: | ZHANG Han |
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| Institution: | College of Life Sciences;Hebei University;Baoding;Hebei 071002 |
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| Abstract: | Objective] To explore the rule of 5-hydroxytryptamine(5-HT) synthesis and metabolism in peripheral blood of suckling piglets with aging.Method] All of 15 British Large White Pigs at 0,5 and 15 days of age were selected as experimental animals,and their serumal concentrations of L-tryptophan(L-Trp),5-HT and 5-hydroxyindoleacetic acid(5-HIAA) in peripheral circulatory system were determined synchronously by reversed high performance liquid chromatography method with UV.Results] The results showed that the ... |
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| Keywords: | 5-hydroxytryptamine L-tryptophan 5-hydroxyindoleacetic acid Peripheral circulatory system Suckling piglets |
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