乌苏里瓦韦不同提取物的抗炎作用研究

目的]对比研究乌苏里瓦韦不同溶剂提取物的抗炎作用。方法]以浓度70％乙醇与蒸馏水作为溶剂，采用回流提取法对乌苏里瓦韦进行提取，建立二甲苯致小鼠耳廓肿胀模型评价乌苏里瓦韦各提取液的抗炎作用。结果]鸟苏里瓦韦水提液高、中剂量组和浓度70％醇提液高剂量组对二甲苯致小鼠耳肿胀均有抑制作用，且浓度70％醇提液高剂量组抑制作用最为显著（P〈0．01）。结论]乌苏里瓦韦水提液在正常用量（中剂量）下抗炎效果最明显，与相关记载的用法用量及主治相符。

Study on Anti-inflammatory Effect of the Different Extracts of Lepisorus ussuriensis

Objective] To study the anti-inflammatory effects among the different solvent extracts of Lepisorus ussuriensis. Method ]With 70% ethanol and distilled water as solvent, reflux extraction method was used to extract kepisorus ussuriensis. The anti-inflammatory effect was ob-served by means of dimethylbenzene inducing mouse ear edema model. Result ] Medium and large dose group of the water extract and large dose group of the alcohol extract of Lepisorus ussuriensis all significantly inhibited swelling of mouse ear and large dose group of the alcohol extract had the most significant anti-inflammatory effect（ P 〈 0. 01 ）. Conclusion] Lepisorus ussuriensis has the most obvious anti-inflammatory effect in me-dium water extract, which is consistent with relevant recorded usage, dosage and indication.