RNA二级结构预测及其在分子分类研究中的应用

文中通过比较RNA二级结构与一级结构和三维结构的差异,说明了RNA二级结构用于系统发育和分子分类研究的优点,并介绍了目前构建RNA二级结构的常用方法以及各种方法的优缺点,并对用于RNA二级结构折叠的软件作了简单介绍。最后从4个方面详细阐述了RNA二级结构在分子分类研究中的应用,即:RNA二级结构应用于分子分类研究的理论和方法;应用RNA二级结构分类与形态分类的区别;三种RNA二级结构在分子分类中的研究现状;RNA二级结构对序列信息的校正与补充。

Prediction and Application of RNA Secondary Structure in the Study of Molecular Taxonomy

Through comparing the differences among the RNA secondary,primary and tertiary structures,the advantages of RNA secondary structure in the phylogenesis and molecular taxonomy were illustrated.The common methods of designing RNA secondary structure,as well as their strongpoints and shortcomings were discussed,the software adopted in the folding of RNA secondary structure was briefly introduced.Finally the application of RNA secondary structure in molecular taxonomy research was analyzed from four aspects,including the applied theory and methods of RNA secondary structure,the differences between taxonomic classification and RNA secondary structure classification,the research progress on the application of three RNA secondary structures in molecular taxonomy,and the amending and supplement of sequence information by RNA secondary structure.