| 不同固体剂型元胡止痛制剂的溶出度考察 |
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| 引用本文： | 万军,闫翠起,翟羽佳,贾程程.不同固体剂型元胡止痛制剂的溶出度考察[J].安徽农业科学,2010,38(35):20501-20502. |
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| 作者姓名： | 万军 闫翠起 翟羽佳 贾程程 |
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| 作者单位： | 西南交通大学生命科学与工程学院; |
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| 基金项目： | 中央高校基本科研业务费专项资金资助项目 |
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| 摘 要： | 目的]比较9个厂家不同固体剂型元胡止痛制剂的溶出度,为临床用药提供参考。方法]采用紫外分光光度法测定延胡索乙素的吸光度值,转篮法测定溶出度,并以威布尔分布模型拟合溶出参数。结果]9个厂家不同固体剂型中元胡止痛片剂和胶囊剂的溶出度、崩解时限均符合2005年版《中国药典》规定,T50与崩解时限间无显著相关性（P〉0.05）。结论]研究所用方法简便、快速、稳定性好、结果准确,可用于药品制剂的质量控制。
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| 关 键 词： | 元胡止痛片 胶囊 溶出度 紫外分光光度法 |
Studies on Dissolution Rates of Yuanhu Zhitong Preparation in Different Solid Dosage Forms |
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| WAN Jun et al.Studies on Dissolution Rates of Yuanhu Zhitong Preparation in Different Solid Dosage Forms[J].Journal of Anhui Agricultural Sciences,2010,38(35):20501-20502. |
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| Authors: | WAN Jun |
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| Institution: | WAN Jun et al(Life Science & Engineering College of South-west Jiao-tong University,Chengdu,Sichuan 610031) |
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| Abstract: | Objective]In order to compare the dissolution rates of Yuanhu Zhitong tablets and capsules to offer reference for clinical medication.Methods]The absorbance of tetrahydropalmatine was measured by ultraviolet spectrophotometry.The dissolution was determined by rotating basket method,the parameters on stripping curves were fitted by Weibull distribution model.Results]All the dissolution rates and disintegration time of Yuanhu Zhitong tablets and capsules preparations from these manufactures meet the standa... |
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| Keywords: | Yuanhu Zhitong tablets Capsules Dissolution rate Ultraviolet spectrophometry |
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