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微血管周细胞与糖尿病视网膜病变中西医研究进展
作者姓名:赵永旺  刘峥嵘  秦裕辉
作者单位:湖南中医药大学, 湖南 长沙 410208;永州职业技术学院附属医院, 湖南 永州 425000,湖南省中医研究院附属医院, 湖南 长沙 410007,湖南中医药大学, 湖南 长沙 410208
基金项目:国家自然科学基金面上项目(81473737)
摘    要:大量的实验研究已经证实,微血管周细胞在糖尿病视网膜病变早期防治中扮演重要角色。为了观察和研究糖尿病视网膜病变早期微血管周细胞结构和功能变化,本文对近些年微血管周细胞的起源、形态分布、生理功能、细胞培养与鉴定、周细胞凋亡与糖尿病视网膜病变关系以及中医药防治糖尿病视网膜病变的研究进展进行综述,以期为糖尿病视网膜病变的周细胞研究及早期防治提供一种新思路。

关 键 词:微血管  周细胞  糖尿病视网膜病变  中药  早期防治
收稿时间:2018/9/3 0:00:00

Research Advances in Microvascular Pericytes and Diabetic Retinopathy in Traditional Chinese Medicine and Western Medicine
Authors:ZHAO Yongwang  LIU Zhengrong and QIN Yuhui
Institution:Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The Affiliated Hospital of Yongzhou Vocational Technical College, Yongzhou, Hunan 425000, China,The Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha, Hunan 410007, China and Hunan University of Chinese Medicine, Changsha, Hunan 410208, China
Abstract:A large number of experimental studies have demonstrated that microvascular pericytes play a major role in the early prevention and treatment of diabetic retinopathy. To observe and study the structural and functional changes of microvascular pericytes in early diabetic retinopathy, we review the literature on the origin, morphological distribution, physiological function, and cell culture and identification of microvascular pericytes, the relationship between pericyte apoptosis and diabetic retinopathy, and the traditional Chinese medicine prevention and treatment of diabetic retinopathy, so as to provide new insights into the pericyte studies and the early prevention and treatment of diabetic retinopathy.
Keywords:microvascular  pericyte  diabetic retinopathy  traditional Chinese medicine  early prevention and treatment
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