蜂胶对高脂血症大鼠血液和肝脏脂质的影响

测定和比较蜂胶水提液、醇提液对实验性高脂血症SD大鼠血液和肝脏脂质的影响. 结果表明:蜂胶醇提液和水提液均能有效抑制高脂血症SD大鼠血清中的甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)、谷丙转氨酶(GPT)、谷草转氨酶(GOT)的升高,并且能有效抑制肝脏组织中的TC、TG、MDA的升高,但对血清中的高密度脂蛋白(HDL-C)、超氧化物歧化酶(SOD)、丙二醛(MDA)、一氧化氮(NO)的影响不明显;蜂胶醇提液能有效降低高脂血症SD大鼠的体重、肝重及肝指数,蜂胶水提液对体重、肝重及肝指数的影响则不显著. 表明蜂胶能够改善高脂血症大鼠的脂质代谢,并具有一定的抗氧化作用.

Effects of propolis on blood lipid and liver lipid of hyperlipidemic SD rats

Effects of proplis extracted by water and by ethanol on blood lipid and liver lipid of hyperlipidemic Sprague Dawley (SD) rats were studied. The results showed that either of the extracted propolis had significant inhibitory effect on the level of triglyceride (TG), total cholesterol (TC), LDL-C, GPT and GOT in serum, and TC, TG and MDA in liver, but were ineffective on HDL-C, MDA, SOD and NO levels in serum. Ethanol extracted propolis also reduced the body weight, liver weight and liver index of hyperlipidemic SD rats, while water extracted propolis were adiaphorous. Thus the two extracts are believed to be helpful in improving lipid metabolization of hyperlipidemic SD rats and provided with antioxidant activity.