甘露寡糖对断奶仔猪肠道主要菌群和免疫机能的影响

选择健康的 35日龄断奶仔猪 4 8头 ,随机分为两组 ,每组 3圈 ,每圈 8头。一组饲喂含 0 3%甘露寡糖 +基础日粮 ,另一组饲喂基础日粮 ,进行了为期 2 8d的饲养试验。从甘露寡糖对断奶仔猪肠道主要菌群和免疫机能的影响着手 ,探讨甘露寡糖对断奶仔猪腹泻的防治效果和机理。结果表明 ,甘露寡糖 (MOS)降低仔猪腹泻频率为5 4 % ;在提高机体免疫方面 ,MOS对淋巴细胞数 (CD3 )和外周血液IgG含量均较对照组差异极显著 (P <0 0 1) ;MOS组血清SOD、PSH -PX活性均较对照组差异极显著 (P <0 0 1)。在生产性能方面 ,甘露寡糖组仔猪日增重和饲料报酬均有明显的提高 ;与对照组相比 ,甘露寡糖可以显著降低盲肠、结肠大肠杆菌浓度 (P <0 0 5 ) ;同时显著提高盲肠乳酸杆菌和双歧杆菌浓度 (P <0 0 5 ) ,但对结肠乳酸杆菌和双歧杆菌数影响不显著 (P >0 0 5 )。

Effect of Mannanoligosaccharide on Intestinal Bacteria Populations and Immune Response of Weaned Pigs

Forty eight 35-year-old weaned pigs were divided into two groups randomly. The control group was fed with basal diet,the other group was fed with 0 3% Mannanoligosaccharide+basal diet. In the course of the experiment for 28 days, weanling pigs were observed; feed intake and body weight per weanling pig were recorded; serum and the whole blood of pigs were collected to be analyzed. At the same time, six piglets of each group were selected on 42-year-old to measure the caecal and colonic microflora population and pH. The result showed that Group MOS made diarrhea frequency of weanling pigs decrease by 54 percent; Group MOS had significant effect (P<0 01) on the number of T lymphocyte (CD\-3) and IgG content in peripheral blood. Group MOS had significant effect (P<0 01) on activities of SOD and GSH-PX in serum of pigs. Daily gain of gummer and feed conversion efficiency increased in treatment groups. caecal and colon E.coli concentration of MOS group was lower(P<0 05) than that of the control group; caecal lactobacilli and bifidobacteria concentration were higher(P<0 05),but colon lactobacilli and bifidobacteria concentration had no significant difference(P>0 05)in contrast with the control group.