Urinary Concentrations of Hydroxyproline and 3—Methyl Histidine in Postpartum Cow

1 Introductionlt has been shown in rat (Harkness and Harknees, 1954), human (Montford and PerezTamayo, l961 )and cattle (Kaidi, l989)that the increase in the weight of the uterus during..pregnancy is associated with an increase in the collagen content of the uterus. Especially,thecervix of thhe cow is composed of collagen by 85% in non --pregnant status. However, themechanisms involved in stimulating col1agen synthesis are unknown. At the same time whenuterus i11creased in collagen content d…

Urinary Concentrations of Hydroxyproline and 3 Methyl Histidine in Postpartum Cow

The urinary concentrations of hydroxyproline (HYPRO)and 3－methyl histidine (3－MEH1S ) were de termined in 16 Chinese－Holstein cows. The objectives of the experiment were to find out thhe relationship between collagen and myosin ddegradation and uterine involution in the postpartum cow. The results in the experiment showed that the mean concentrations of HYPRO and 3－MEHIS were 138.92±22.99 and 37.09 ± 3.90 nmol · mL-1 ,respectively ,for the cows during the days between 60～90 postpartum ,and for the covs immediately after calving the concentrations of HYPRO and 3－MEHIS reduced from 284.30 and 65.I8 nmol · mL-1 on the day one after calving to the normal level of 109.18 and 33.51 nmol · mL－1 on the day 50 post partum ,respectively. There was a good correlation between the urinary concentrations of both HYPRO and 3 －MEHIS and the diameters of the involuting uterus ( r ＝0.79).