| 胚胎晚期暴露脂多糖对中年CD-1小鼠背侧海马SUMO-3含量的影响 |
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| 引用本文： | 杨启纲,陈贵海.胚胎晚期暴露脂多糖对中年CD-1小鼠背侧海马SUMO-3含量的影响[J].安徽农业大学学报,2017,44(2):214-217. |
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| 作者姓名： | 杨启纲 陈贵海 |
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| 作者单位： | 安徽医科大学第一附属医院重症医学科,合肥,230022;安徽医科大学附属巢湖医院神经内科和全科医学科,合肥,238000 |
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| 基金项目： | 国家自然科学基金（81370444）和安徽省高校自然科学研究项目（KJ2015A126）资助。 |
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| 摘 要： | 为探讨胚胎晚期暴露细菌脂多糖(LPS)的中年CD-1小鼠背侧海马的类泛素化蛋白(SUMO-3)含量有无年龄相关性改变。采用免疫组织化学技术检测LPS暴露组和对照组CD-1小鼠背侧海马DG区、CA1区和CA3区各亚层的SUMO-3表达。结果表明,两组间各区各亚层的SUMO-3含量无明显差异。
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| 关 键 词： | 细菌脂多糖 免疫组织化学 背侧海马 类泛素化蛋白 |
Effects of lipopolysaccharide on the SUMO-3 levels in doral hippocampus of middle-aged CD-1 mice during late embryon |
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| YANG Qigang and CHEN Guihai.Effects of lipopolysaccharide on the SUMO-3 levels in doral hippocampus of middle-aged CD-1 mice during late embryon[J].Journal of Anhui Agricultural University,2017,44(2):214-217. |
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| Authors: | YANG Qigang and CHEN Guihai |
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| Institution: | Department of Critical Care Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei 230022 and Department of Neurology and General Practice, Chaohu Hospital Affiliated of Anhui Medical University, Hefei 238000 |
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| Abstract: | To explore the SUMO-3 levels in different subregions of dorsal hippocampus (DH) in the middle-aged CD-1 mice, we used immunohistochemical method to detect the expression of SUMO-3 in different DH subregions. The results showed that, in all sublayers of hippocampal DG, CA1 and CA3 regions, the SUMO-3 level of LPS-group was similar to those in the middle-aged mice of the control-group. There were no significant differences between the two groups in each sublayer of DG, CA1 and CA3 regions. |
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| Keywords: | bacterial lipopolysaccharide immunohistochemical method dorsal hippocampus small ubiquitin-related modifier-3 |
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