基于图像处理技术的生物反应器浓度检测系统的开发

发酵过程生物参数的在线检测,是获得发酵过程生物信息的重要手段,也是进行合理最优控制的基础。但是,目前许多生物量只能离线检测,不能够为实时的控制系统利用。因此提出了基于图像处理技术的生物反应器浓度在线检测系统,系统由反应液循环与控制装置、反应液浓度光学检测装置、图像采集与处理装置、计算机以及相应的处理软件组成。通过与分光光度计的实验比较,证实了所设计的系统可以用于生物反应器浓度的在线测量,为实现发酵过程生物参数的在线检测提供了值得借鉴的设计思路和实现方法。

Development of concentration measurement system in bioreactor based on image processing

Measurement and monitoring of fermentation parameter is a very important way for obtaining the information of fermentation process, and also is the basis of optimal control. But, until now, most bioinformation is obtained offline, and the bio-information can not be used for control system on-line. In this paper, an on-line measurement system is developed based on the image processing technique. The developed system includes circulation and control part of solution, optical measurement part of solution, image catch and process part, computer and the software programme. The developed measurement system is compared with an existing spectrometer. The experiment results proved the proposed method and system can be used in on-line measurement system for development of other analytical instruments.