金花茶花中木脂素类化学成分的分析

为了研究金花茶花中的木脂素类化学成分，采用硅胶柱、Sephadex LH-20凝胶柱、C18反相色谱柱、半制备高压液相色谱等色谱方法对金花茶花的化学成分进行分离纯化，同时运用1H-NMR，13C-NMR，ESI-MS等多种波谱技术鉴定化合物的结构。共得到8个木脂素类化合物，分别鉴定为:1）桉脂素，2）(+)-diasyringaresinol，3）(+)-isoeucommin A，4）Pinoresinol 4-O-glucoside，5）7S, 8R, 8 ′R-(-)-lariciresinol-4′-O-D-glucopyranoside，6）(+)-Isolariciresinol 9-O-β-D-glucopyranoside,7）(+)-Isolariciresinol 9′-O-β-D-glucopyranoside，8）3′, 4-O-dimethylcedrusin。本实验8个木脂素类化合物均为首次从该植物中分离得到。

Chemical Composition of Lignans from the Flowers of Camellia nitidissima

Flowers of Camellia nitidissima Chi were extracted, and their chemical constituents were then isolated and purified by silica gel, Sephadex LH-20 gel, C18 reversed silica gel, and semi-preparative HPLC. The structures of their chemical constituents were determined by using iH-NMR, 13C-NMR and ESI-MS spectra. Eight lignans were identified from the extracts of the flowers, and their structures were elucidated from the spectra as: eudesmin (1), (+)-diasyringaresinol (2), (+)-isoeucommin A (3), Pinoresinol 4-O-glucoside (4), 7S, 8R, 8′R-(-)-lariciresinol-4′-O-D-glucopyranoside (5), (+)-Isolariciresinol 9-O-β-D-glucopyranoside (6), (+)-Isolariciresinol 9′-O-β-D-glucopyranoside (7), and 3′, 4-O-dimethylcedrusin (8). All these chemical compounds were isolated from C. nitidissima Chi for the first time.