| 烹调胡麻油油烟对小鼠肝、肺组织的损伤实验 |
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| 引用本文： | 王小玻,高建培,王彬,胡燕琴,罗玲玲.烹调胡麻油油烟对小鼠肝、肺组织的损伤实验[J].热带生物学报,2010,1(2):121-124. |
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| 作者姓名： | 王小玻 高建培 王彬 胡燕琴 罗玲玲 |
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| 作者单位： | 王小玻,高建培,王彬(昆明理工大学,环境科学与工程学院,云南,昆明,650093);胡燕琴,罗玲玲(宁夏大学,资源环境学院,宁夏,银川,750021) |
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| 摘 要： | 采取静式吸入染毒法,用烹调油烟对小鼠进行亚急性连续染毒,并通过测试小鼠肝、肺组织匀浆中的SOD活性及MDA含量和小鼠血液中血清SOD活性及MDA的含量,探讨烹调油烟对小鼠肝、肺组织的损伤作用。结果表明,烹调油烟可使(1)肝、肺组织SOD活性下降,MDA含量增高;(2)血液中SOD活性下降,MDA含量增高;(3)染毒实验组小鼠平均体质量比阴性对照组小鼠体质量要轻。
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| 关 键 词： | 烹调油烟 超氧化物歧化酶 丙二醛 肺组织损伤 |
Damages of the Liver and Lung Tissue of Mice Caused by Cooking Flaxseed Oil Fumes |
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| WANG Xiao-bo,GAO Jian-pei,WANG Bin,HU Yan-qin,LUO Ling-ling.Damages of the Liver and Lung Tissue of Mice Caused by Cooking Flaxseed Oil Fumes[J].Journal of Tropical Biology,2010,1(2):121-124. |
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| Authors: | WANG Xiao-bo GAO Jian-pei WANG Bin HU Yan-qin LUO Ling-ling |
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| Institution: | 1. School of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650093, China; 2. School of Resource and Environment, Ningxia University, Yinchuan 750021, China) |
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| Abstract: | To analysis the damages of the cooking oil fumes on the lung tissue and liver tissue, the activities of superoxide dismutase （SOD） and the concentration of malondialdehyde （MDA） in serum, liver tissue and lung tissue were determined. The results indicated that SOD activities in lung and liver tissue of the exposure mice, in which the cooking oil fumes arc inhaled （43.44 ±10.46）mg · m^-3 ,40 min per day,10 day;20 day,30 day], are lower than that of control significantly, in which the fresh air are inhaled, while MDA concentration are high- er than that of control significantly; SOD activities in serum of the exposure mice are lower than that of control significantly, while MDA concentration are higher than that of control significantly; the body weights of exposure mice are lower than that of control significantly . |
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| Keywords: | cooking oil fumes （COF） superoxide dismutase （SOD） malondialdehyde （MDA） damage lung tissue |
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