| 利奈唑胺治疗耐甲氧西林金黄色葡萄球菌肺炎的疗效及影响因素分析 |
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| 引用本文： | 谭世繁,张雄,罗宁,陈春杰,王铮,陈智华,黄壮志.利奈唑胺治疗耐甲氧西林金黄色葡萄球菌肺炎的疗效及影响因素分析[J].湛江医学院学报,2011,29(3):257-259. |
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| 作者姓名： | 谭世繁 张雄 罗宁 陈春杰 王铮 陈智华 黄壮志 |
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| 作者单位： | 谭世繁 (广东省茂名市人民医院,广东茂名,525000) ； 张雄 (广东省茂名市人民医院,广东茂名,525000) ； 罗宁 (广东省茂名市人民医院,广东茂名,525000) ； 陈春杰 (广东省茂名市人民医院,广东茂名,525000) ； 王铮 (广东省茂名市人民医院,广东茂名,525000) ； 陈智华 (广东省茂名市人民医院,广东茂名,525000) ； 黄壮志 (广东省茂名市人民医院,广东茂名,525000) ； |
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| 摘 要： | 目的 分析利奈唑胺治疗耐甲氧西林金黄色葡萄球菌(MRSA)肺炎的疗效、影响因素及安全性.方法 回顾性分析41例利奈唑胺治疗MRSA肺炎的临床资料.结果 利奈唑胺治疗MRSA肺炎的有效率为78.0%,细菌清除率为73.2%,不良反应率为2.4%.血培养阳性、合并感染性心内膜炎者的临床疗效及细菌清除率明显降低(P＜0.05...
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| 关 键 词： | 利奈唑胺 肺炎 耐甲西林金黄色葡萄球菌 |
Therapeutic efficacy and influential factors for methicillin resistant Staphylococcus aureus pneumonia treated by linezolid |
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| TAN Shi-fan,ZHANG Xiong,LUG Ning,CHEN Chun-jie,WANG Zheng,CHEN Zhi-hua,HUANG Zhuang-zhi.Therapeutic efficacy and influential factors for methicillin resistant Staphylococcus aureus pneumonia treated by linezolid[J].Journal of Guangdong Medical College,2011,29(3):257-259. |
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| Authors: | TAN Shi-fan ZHANG Xiong LUG Ning CHEN Chun-jie WANG Zheng CHEN Zhi-hua HUANG Zhuang-zhi |
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| Institution: | (Maoming People＇ s Hospital, Maoming 525000, China) |
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| Abstract: | Objective To analyze the curative effect, influential factors and safety of linezolid for treating methicillin- resistant Staphylococcus aureus （MRSA） pneumonia. Methods Clinical data of 41 MRSA peneumonia patients underwent linezolid treatment were retrospectively analyzed. Results The rates of curative effect, bacteria clearance and adverse reaction were 78.0%, 73.2% and 2.4%, respectively. The positive blood culture and infective endocarditis reduced therapeutic efficacy and bacteria clearance （P〈0.05）. Conclusion Linezolid is effective and safe for treating MRSA pneumonia, but its therapeutic efficacy can be influenced by positive blood culture and infective endocarditis. |
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| Keywords: | linezolid pneumonia methicillin resistant Staphylococcus aureus |
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