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冠心病患者血浆中分子物质和过氧化脂质水平的变化
引用本文:吴铿,岑治勋,祝其锋,吴波.冠心病患者血浆中分子物质和过氧化脂质水平的变化[J].湛江医学院学报,1993(Z1).
作者姓名:吴铿  岑治勋  祝其锋  吴波
作者单位:湛江医学院附属医院内科 (吴铿),湛江医学院附属医院老年病科 (岑治勋),湛江医学院生化教研室 (祝其锋),湛江医学院生化教研室(吴波)
摘    要:本文检测113例冠心病患者血浆中分子物质和过氧化脂质水平,结果显示:劳累性心绞痛患者血浆中分子物质水平显著升高(P<0.05),血浆过氧化脂质水平显著降低(P<0.05);自发性心绞痛和缺血性心脏病的心力衰竭、急性心肌梗塞患者血浆中分子物质和过氧化脂质水平都显著升高(P<0.05),尤以急性心肌梗塞患者血浆中分子物质和过氧化脂质水平升高更为显著(P<0.05).本文结果表明,冠心病患者血浆中分子物质和过氧化脂质水平的变化与病变程度有关,有助于冠心病病情和预后的判断.

关 键 词:冠心病  中分子物质  过氧化脂质类

THE CHANGES OF PLASMA LEVEL OF MIDDLE MOLECULE AND LIPID PEROXIDE IN PATIENTS WITH CORONARY HEART DISEASE
Wu Keng Cen Zhixun Zhu Qifeng Wu Bo.THE CHANGES OF PLASMA LEVEL OF MIDDLE MOLECULE AND LIPID PEROXIDE IN PATIENTS WITH CORONARY HEART DISEASE[J].Journal of Guangdong Medical College,1993(Z1).
Authors:Wu Keng Cen Zhixun Zhu Qifeng Wu Bo
Institution:Wu Keng Cen Zhixun Zhu Qifeng Wu Bo Department of Internal Medicine,The Affiliated Hospital Department of Gerontology,The Affiliated Hospital Department of Biochemistry
Abstract:The plasma level of middle molecule (mm) and lipid peroxide (LPO) was teste.d in 113 patients with coronary heart disease. The results showed; (1)the level of mm was significantly elevated(P<0. 05),while that of the LPO significantly decreased(P<0. 05)in patients with angina pectoris induced by exhaustion5 (2)the level of mm and LPO was significantly elevated (P<0. 05)in patients with angina occurred spontaneously and those with heart failure or a-cute myocardial infarction due to ischemic cardiac disease,especially obvious in cases with the later disease. The results suggest that the change of plasma level of mm and LPO in anginal patients is related with the seveveness of the disease and helpful assessment of the condition and its prognosis.
Keywords:coronary heart disease  middle molecules  lipid peroxides
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