| 紫苏叶提取物对高脂血症家兔血脂及脂质过氧化的影响（英文） |
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| 作者单位： | TAN Jian-min1，CHEN Juan-hua1，XU Zai-pin1，HUO Xin1，DENG Xiao-yan2，ZHANG Di1，JIAN Xiu-hua3 1.Department of Veterinary Medicine，College of Animal Science，Guizhou University，Guiyang 550025;2.Department of Bioengineering，Beijing University of Aeronautics & Astronautics，Beijing 100083;3.Agricultural bureau of Huaxi District，Guiyang 550025 |
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| 摘 要： | Objective] The preventive and therapeutic effects of Folium perillae extract(FPE)on hyperlipemia induced by feeding rabbit with high fat forage were observed.Method] The high fat and cholesterol diet were adopted to create the hyperlipemia model of rabbit.The rabbits were randomly and equally divided into 5 groups which were NC(normal control)group,HLM(high lipid model)group,LFPE,MFPE and HFPE group(low,middle,high dosage of FPE were 0.17 g/kg,0.5 g/kg and 1.5 g/kg respectively).The contents of TC,TG,LDL-C,HDL-C,MDA and the activity of SOD in serum were detected respectively.Result] The three FPE groups could decrease the contents of TC,TG,LDL-C,MDA significantly(P<0.01)compared with these of HLM group,and the contents of HDL-C(P<0.01))and the activity of SOD(P<0.05)in serum was increased significantly.Conclusion] FPE could regulate blood-fat and counteract lipid peroxidation.
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The Effects of Folium Perillae Extract on Blood Fat and Lipid per Oxidation of Rabbit with Hyperlipemia |
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| Authors: | TAN Jian-min CHEN Juan-hua XU Zai-pin HUO Xin DENG Xiao-yan ZHANG Di JIAN Xiu-hua |
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| Institution: | TAN Jian-min1,CHEN Juan-hua1,XU Zai-pin1,HUO Xin1,DENG Xiao-yan2,ZHANG Di1,JIAN Xiu-hua3 1.Department of Veterinary Medicine,College of Animal Science,Guizhou University,Guiyang 550025,2.Department of Bioengineering,Beijing University of Aeronautics & Astronautics,Beijing 100083,3.Agricultural bureau of Huaxi District,Guiyang 550025 |
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| Abstract: | Objective] The preventive and therapeutic effects of Folium perillae extract(FPE)on hyperlipemia induced by feeding rabbit with high fat forage were observed.Method] The high fat and cholesterol diet were adopted to create the hyperlipemia model of rabbit.The rabbits were randomly and equally divided into 5 groups which were NC(normal control)group,HLM(high lipid model)group,LFPE,MFPE and HFPE group(low,middle,high dosage of FPE were 0.17 g/kg,0.5 g/kg and 1.5 g/kg respectively).The contents of TC,TG,LDL-C,HDL-C,MDA and the activity of SOD in serum were detected respectively.Result] The three FPE groups could decrease the contents of TC,TG,LDL-C,MDA significantly(P<0.01)compared with these of HLM group,and the contents of HDL-C(P<0.01))and the activity of SOD(P<0.05)in serum was increased significantly.Conclusion] FPE could regulate blood-fat and counteract lipid peroxidation. |
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| Keywords: | Folum perillae extract(FPE) Blood fat Malonaldehyde(MDA) Superoxide dismutase(SOD) |
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