| 非洲猪瘟病毒VP73蛋白的B细胞表位预测（英文） |
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| 作者单位： | LI Qian1，YAO Shu-xia2 1.Science and Engineering College of Chemistry and Biology，Yantai University，Yantai 264005;2.College of Life Science and Technology，Guangxi University，Nanning 530005 |
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| 摘 要： | Objective] The B cell epitopes for VP73 protein of African swine fever virus was predicted.Method]Based on the analysis of the amino acid sequence and the flexible regions of VP73 protein,the B cell epitopes for VP73 protein of African swine fever virus were predicted by method of Kyte-Doolittle,Emini and Jameson-Wolf.Result]The B cell epitopes were located at or adjacent to the N-terminal No.11-18,26-48,73-82,136-150,159-174,181-189,191-210,247-276,279-295,313-323 and 382-392.Conclusion]The multi-parameters analytic method was adopted to predict the B cell epitopes for VP73 protein of African swine fever virus,which laid solid foundation for further characterizing the protein of VP73 and researching epitope vaccine.
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The Prediction of B Cell Epitopes for VP73 Protein of African Fever Virus |
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| Authors: | LI Qian YAO Shu-xia Science and Engineering College of Chemistry and Biology Yantai University Yantai College of Life Science and Technology Guangxi University Nanning |
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| Institution: | LI Qian1,YAO Shu-xia2 1.Science and Engineering College of Chemistry and Biology,Yantai University,Yantai 264005,2.College of Life Science and Technology,Guangxi University,Nanning 530005 |
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| Abstract: | Objective] The B cell epitopes for VP73 protein of African swine fever virus was predicted.Method]Based on the analysis of the amino acid sequence and the flexible regions of VP73 protein,the B cell epitopes for VP73 protein of African swine fever virus were predicted by method of Kyte-Doolittle,Emini and Jameson-Wolf.Result]The B cell epitopes were located at or adjacent to the N-terminal No.11-18,26-48,73-82,136-150,159-174,181-189,191-210,247-276,279-295,313-323 and 382-392.Conclusion]The multi-parameters analytic method was adopted to predict the B cell epitopes for VP73 protein of African swine fever virus,which laid solid foundation for further characterizing the protein of VP73 and researching epitope vaccine. |
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| Keywords: | African swine fever virus VP73 protein B cell epitope |
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